# Revision and postoperative complication rates of conversion total hip arthroplasty after cephalomedullary nailing of intertrochanteric femur fractures: a systematic review and meta-analysis

**Authors:** Harmon S. Khela, Harsh Wadhwa, Henry J. Wong, L. Henry Goodnough

PMC · DOI: 10.1007/s00590-026-04681-6 · European Journal of Orthopaedic Surgery & Traumatology · 2026-02-19

## TL;DR

This study finds that conversion total hip arthroplasty after failed femur fracture surgery has a 6.7% revision rate and higher risks compared to standard hip replacement.

## Contribution

The study provides the first comprehensive meta-analysis of complication rates for cTHA after cephalomedullary nailing of intertrochanteric fractures.

## Key findings

- Overall revision rate after cTHA was 6.7%, with cemented implants showing lower complication rates than cementless ones.
- Cemented stems had significantly lower infection and dislocation rates compared to cementless and diaphyseal cementless stems.
- Periprosthetic fracture rates were 5.9% overall, with cemented implants having the lowest rate at 3.2%.

## Abstract

Management of failed intertrochanteric (IT) fracture fixation often requires conversion total hip arthroplasty (cTHA), but complication and reoperation rates remain poorly characterized in the literature. This study aimed to characterize revision and postoperative complication rates for cTHA after cephalomedullary nailing of IT fractures.

A systematic review and meta-analysis was conducted following PRISMA guidelines. PubMed and Embase were queried for studies examining cTHA outcomes after prior cephalomedullary nailing for IT fractures. The primary outcome was revision rate, while secondary outcomes included rates of infection, dislocation, subsidence, and periprosthetic fracture (PPF). A random-effects model was employed to pool overall and implant-specific complication rates.

Seventeen studies with 1,253 cTHA patients met inclusion criteria. Implant type was specified in 799 cases: primary cementless (47.9%), primary cemented (38.8%), diaphyseal cementless (12.0%), and diaphyseal cemented (1.3%). Overall revision rate was 6.7%, infection rate was 3.3%, dislocation rate was 4.5%, and PPF rate was 5.9%. Subgroup analysis across six studies allowed for comparison between primary cementless (n = 265), primary cemented (n = 220), and diaphyseal cementless (n = 17) implants. Cemented stems had a revision rate of 2.4%, an infection rate of 1.8%, a dislocation rate of 2.4%, a subsidence rate of 3.8%, and a PPF rate of 3.2%, compared to cementless (10.1%, 2.8%, 3.3%, 8.1%, 7.7%) and diaphyseal cementless (7.0%, 8.9%, 18.3%, 7.0%, 7.0%) stems.

cTHA is an effective salvage option for failed IT fracture fixation but carries notable postoperative risks compared to primary THA. Optimal outcomes require careful femoral component selection tailored to patient-specific factors.

The online version contains supplementary material available at 10.1007/s00590-026-04681-6.

## Full-text entities

- **Diseases:** dislocation (MESH:D004204), Cardiovascular complications (MESH:D002318), Infection (MESH:D007239), atrial fibrillation (MESH:D001281), tumor (MESH:D009369), pulmonary embolism (MESH:D011655), femur fractures (MESH:D000092524), bone (MESH:D001847), urinary tract infections (MESH:D014552), PPF (MESH:D057068), blood loss (MESH:D016063), osteoporotic (MESH:D058866), injuries (MESH:D014947), complication (MESH:D008107), heterotopic ossification (MESH:D009999), pain (MESH:D010146), fracture (MESH:D050723), post-traumatic arthritis (MESH:D016918), cTHA (MESH:D003291), postoperative (MESH:D019106), abductor tendon deficiencies (MESH:D052256), hip arthroplasty (MESH:D025981), IT fracture (MESH:D006620)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12920368/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12920368/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12920368/full.md

---
Source: https://tomesphere.com/paper/PMC12920368