# Primary Peritoneal Tuberculosis in an Immunocompetent Patient: A Case Report

**Authors:** Vijayakumaran Yanusha, Pakkiyaretnam Mayurathan

PMC · DOI: 10.7759/cureus.101940 · Cureus · 2026-01-20

## TL;DR

A 33-year-old man with no immune issues was diagnosed with rare peritoneal tuberculosis after abdominal swelling led to a biopsy.

## Contribution

This case report highlights the diagnostic challenges of peritoneal TB in immunocompetent individuals and underscores the need for early suspicion and treatment.

## Key findings

- Peritoneal TB was confirmed in an immunocompetent patient via omental biopsy.
- Anti-tuberculous therapy successfully resolved ascites in the patient.
- The case emphasizes the importance of early diagnosis in rare TB manifestations.

## Abstract

Tuberculosis (TB) is endemic in Sri Lanka but is associated with a comparatively low overall disease burden. Pulmonary TB is the most common manifestation among immunocompetent individuals, whereas peritoneal TB is rare and presents significant diagnostic challenges due to nonspecific clinical features such as abdominal distension, chronic diarrhoea, and ascites. We report the case of a 33-year-old immunocompetent male who presented with progressive, painless abdominal distension. A diagnostic mini-laparotomy with omental biopsy confirmed peritoneal TB. Anti-tuberculous therapy was initiated, resulting in complete resolution of ascites on follow-up. This case highlights the diagnostic difficulty of abdominal TB in immunocompetent patients and emphasizes the importance of maintaining a heightened suspicion and initiating early treatment to improve clinical outcomes.

## Linked entities

- **Diseases:** Tuberculosis (MONDO:0018076)

## Full-text entities

- **Genes:** ADA (adenosine deaminase) [NCBI Gene 100] {aka ADA1}, ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}, SLC17A5 (solute carrier family 17 member 5) [NCBI Gene 26503] {aka AST, ISSD, NSD, SD, SIALIN, SIASD}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}
- **Diseases:** infectious disease (MESH:D003141), intra-abdominal lymphadenopathy (MESH:D000082122), fistula (MESH:D005402), HIV infection (MESH:D015658), tuberculous (MESH:D014390), granulomas (MESH:D006099), TB (MESH:D014376), intestinal obstruction (MESH:D007415), bowel perforation (MESH:D057112), inflammatory bowel disease (MESH:D015212), Abdominal TB (MESH:D000007), leukocytosis (MESH:D007964), weight loss (MESH:D015431), Pulmonary TB (MESH:D014397), infected (MESH:D007239), adhesions (MESH:D000267), organomegaly (MESH:D016878), anemia (MESH:D000740), ascites (MESH:D001201), portal hypertension (MESH:D006975), fever (MESH:D005334), chronic diarrhoea (MESH:D003967), hypoalbuminemia (MESH:D034141), febrile (MESH:D000071072), pleural effusion (MESH:D010996), Peritoneal Tuberculosis (MESH:D014395), malignancies (MESH:D009369), peritoneal carcinomatosis (MESH:D010534), cirrhosis (MESH:D005355), chronic liver disease (MESH:D008107)
- **Chemicals:** Glucose (MESH:D005947), Rifampicin (MESH:D012293), Ethambutol (MESH:D004977), Isoniazid (MESH:D007538), Pyrazinamide (MESH:D011718)
- **Species:** Homo sapiens (human, species) [taxon 9606], Mycobacterium tuberculosis (species) [taxon 1773], Mycobacterium tuberculosis variant bovis (biotype) [taxon 1765], Human immunodeficiency virus 1 (no rank) [taxon 11676], Mycobacterium tuberculosis variant africanum (biotype) [taxon 33894]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12920071/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12920071/full.md

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Source: https://tomesphere.com/paper/PMC12920071