# Atypical Presentation of a Cerebellar Abscess Caused by Streptococcus intermedius: Importance of Early Recognition

**Authors:** Iker F Garcia Contreras, César Vega-López, Daniel A Seniscal Arredondo, Yuscely Flores Jurado, Sandra Rivera

PMC · DOI: 10.7759/cureus.101892 · Cureus · 2026-01-20

## TL;DR

A rare case of a cerebellar abscess caused by Streptococcus intermedius highlights the importance of early diagnosis to avoid misdiagnosis as a tumor.

## Contribution

Highlights the atypical presentation of cerebellar abscesses caused by Streptococcus intermedius and emphasizes the need for early recognition.

## Key findings

- Streptococcus intermedius can cause cerebellar abscesses with features resembling neoplastic lesions.
- Early recognition is critical to avoid delayed treatment due to pseudotumoral behavior.
- Combining clinical, radiological, and microbiological data is essential for accurate diagnosis.

## Abstract

A cerebellar abscess due to Streptococcus intermedius is an uncommon clinical entity that may present with features resembling a neoplastic lesion, making early recognition challenging. S. intermedius, a member of the Streptococcus anginosus group, has a marked ability to induce tissue destruction and trigger a pronounced inflammatory response, ultimately leading to the formation of purulent collections with peripheral enhancement on neuroimaging. Although gram-positive cocci are recognized causes of brain abscesses, involvement of the cerebellum by this organism is rare. Awareness of this atypical clinical presentation is critical, since its pseudotumoral behavior may obscure the underlying infectious etiology and delay appropriate therapy. Integrating clinical manifestations, radiological characteristics, and microbiological confirmation is therefore essential for timely diagnosis and favorable clinical outcomes.

## Linked entities

- **Species:** Streptococcus intermedius (taxon 1338)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** inflammatory (MESH:D007249), Cerebellar Abscess (MESH:D000038), headache (MESH:D006261), motor or visual deficits (MESH:D014786), neoplasia (MESH:D009369), edema (MESH:D004487), nausea (MESH:D009325), febrile (MESH:D000071072), vasogenic edema (MESH:D001929), neoplastic lesion (MESH:D009062), dysarthria (MESH:D004401), cerebellar (MESH:D002526), fever (MESH:D005334), vomiting (MESH:D014839), cavernous angioma (MESH:D006392), dysmetria (MESH:D002524), incoordination (MESH:D001259), infection (MESH:D007239), Brain abscesses (MESH:D001922), gait instability (MESH:D043171), primary brain neoplasms (MESH:D001932), infectious (MESH:D003141), neurological deterioration (MESH:D009422)
- **Chemicals:** succinate (MESH:D019802), Choline (MESH:D002794), lactate (MESH:D019344), metronidazole (MESH:D008795), alanine (MESH:D000409), clindamycin (MESH:D002981), vancomycin (MESH:D014640), ceftriaxone (MESH:D002443), macrolides (MESH:D018942), N-acetylaspartate (MESH:C000179), amino acid (MESH:D000596), cephalosporins (MESH:D002511), creatine (MESH:D003401), fluoroquinolones (MESH:D024841), lipid (MESH:D008055), beta-lactam (MESH:D047090), creatinine (MESH:D003404)
- **Species:** Streptococcus intermedius (species) [taxon 1338], Homo sapiens (human, species) [taxon 9606], Streptococcus anginosus (species) [taxon 1328]
- **Mutations:** T 36 C

## Full text

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## Figures

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12918422/full.md

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Source: https://tomesphere.com/paper/PMC12918422