# Functional Dyspepsia Among Nurses Working Rotating Shifts: Its Prevalence and Associations With Sleep Quality and Stress

**Authors:** Rishit Gupta, Arihant Senthil, Smita Nath, Rajnish K Avasthi, Shrey Chopra, Sukul Khanna

PMC · DOI: 10.7759/cureus.101887 · Cureus · 2026-01-20

## TL;DR

This study finds that 31% of nurses working rotating shifts in India suffer from functional dyspepsia, a digestive disorder linked to poor sleep and high stress.

## Contribution

The study is the first to report FD prevalence among Indian nurses and its strong association with sleep and stress in this population.

## Key findings

- 31% of nurses working rotating shifts had functional dyspepsia, higher than the general Indian population.
- FD was strongly correlated with poor sleep quality (74.2% vs. 43.5%) and high stress levels (83.8% vs. 34.7%).
- No gender differences were found in FD prevalence among the studied nurses.

## Abstract

Background and objective

Functional dyspepsia (FD) is one of the most common functional gastrointestinal disorders that frequently impairs quality of life. Among healthcare professionals, shift work may heighten the risk of developing this condition, likely through its impact on stress levels and sleep quality. This study aimed to determine the prevalence of FD among nurses working rotating shifts in India and to examine its relationship with sleep quality and perceived stress.

Methods

A cross-sectional study was conducted at a tertiary care hospital in New Delhi (January 2022-March 2023). The participating nurses (n=100) completed standardized questionnaires, including the Rome IV criteria for FD diagnosis, Pittsburgh Sleep Quality Index (PSQI), and Perceived Stress Scale-10 (PSS-10). Statistical analyses included chi-square tests to evaluate associations.

Results

The prevalence of FD in the cohort was 31%, with 12% reporting postprandial distress syndrome (PDS), 10% epigastric pain syndrome (EPS), and 9% both. Poor sleep quality (PSQI ≥5) was observed in 53% of participants, while 50% reported high/very high stress levels as per PSS-10. Significant correlations emerged between FD and poor sleep (74.2% vs. 43.5% in non-FD, p=0.003) and high stress (83.8% vs. 34.7%, p<0.001). Similar trends were observed for PDS and EPS individually. No gender-based differences in FD prevalence were identified.

Conclusions

Rotating shift work is associated with a high FD prevalence (31%) among nurses, surpassing both the estimated prevalence in the general Indian population (30.4%) and figures reported in other countries. Poor sleep quality and elevated stress levels were strongly linked to FD, highlighting occupational health risks in healthcare shift workers. These findings underscore the need for workplace interventions targeting sleep hygiene and stress management. Future longitudinal studies with control groups are warranted to establish causal relationships and devise preventive strategies.

## Full-text entities

- **Diseases:** PDS (MESH:D012128), obesity (MESH:D009765), anxiety (MESH:D001007), psychiatric (MESH:D001523), cancer (MESH:D009369), diabetes (MESH:D003920), sensory dysfunction (MESH:D012678), IBS (MESH:D053560), sleep disturbances (MESH:D012893), pain (MESH:D010146), GI problems (MESH:D012817), GI inflammation (MESH:D007249), bowel disorders (MESH:D012778), ulcerative colitis (MESH:D003093), REM sleep deprivation (MESH:D020187), Dyspepsia (MESH:D004415), hyperalgesia (MESH:D006930), EPS (MESH:C538101), sleep deprivation (MESH:D012892), depression (MESH:D003866), inflammatory bowel disease (MESH:D015212), abdominal symptoms (MESH:D000007), disturbances in the sleep cycle (MESH:D020178), cardiovascular disease (MESH:D002318), Crohn's disease (MESH:D003424), acid peptic disease (MESH:D010437), FGIDs (MESH:D005767), immune system disorders (MESH:D007154), daytime dysfunction (MESH:D006970)
- **Chemicals:** cortisol (MESH:D006854), serotonin (MESH:D012701), Alcohol (MESH:D000438), 5-HIAA (MESH:D006897), melatonin (MESH:D008550)
- **Species:** gut metagenome (species) [taxon 749906], Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116]

## Full text

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## Figures

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## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12917686/full.md

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Source: https://tomesphere.com/paper/PMC12917686