# Primary Pulmonary Marginal Zone Lymphoma Presenting With Asymptomatic Lung Consolidation

**Authors:** Mohammed Al Shuraiqi, B. Jayakrishnan, Mohammed Al Harrasi, Zahra Al Hajri, Radhiya Al Buraidi

PMC · DOI: 10.1155/crpu/7871010 · Case Reports in Pulmonology · 2026-02-18

## TL;DR

A rare case of lung lymphoma was diagnosed in a patient with an incidental lung mass found during a routine checkup.

## Contribution

This case highlights the diagnostic challenge of asymptomatic primary pulmonary marginal zone lymphoma.

## Key findings

- The patient presented with an incidental lung consolidation/mass.
- A tissue diagnosis was necessary to confirm primary pulmonary marginal zone lymphoma.

## Abstract

Pulmonary lymphoma is a rare condition involving the lung characterized by the abnormal proliferation of lymphoid tissue. Patients may either be asymptomatic or exhibit nonspecific clinical presentations and radiologic findings, making diagnosis challenging. Here, we describe a case of a female patient who presented to our clinic with an incidental radiological finding of pulmonary consolidation/mass. The final diagnosis of a primary pulmonary marginal zone lymphoma required a tissue diagnosis.

## Linked entities

- **Diseases:** pulmonary lymphoma (MONDO:0003987)

## Full-text entities

- **Genes:** CD19 (CD19 molecule) [NCBI Gene 930] {aka B4, CVID3}, CD22 (CD22 molecule) [NCBI Gene 933] {aka SIGLEC-2, SIGLEC2}, CCND1 (cyclin D1) [NCBI Gene 595] {aka BCL1, D11S287E, PRAD1, U21B31}, CD5 (CD5 molecule) [NCBI Gene 921] {aka LEU1, T1}, MME (membrane metalloendopeptidase) [NCBI Gene 4311] {aka CALLA, CD10, CMT2T, NEP, SCA43, SFE}, BCL2 (BCL2 apoptosis regulator) [NCBI Gene 596] {aka Bcl-2, PPP1R50}, BCL6 (BCL6 transcription repressor) [NCBI Gene 604] {aka BCL5, BCL6A, LAZ3, ZBTB27, ZNF51}, PAX5 (paired box 5) [NCBI Gene 5079] {aka ALL3, BSAP, PAX-5}, KRT20 (keratin 20) [NCBI Gene 54474] {aka CD20, CK-20, CK20, K20, KRT21}, CD79A (CD79a molecule) [NCBI Gene 973] {aka IGA, IGAlpha, MB-1, MB1}
- **Diseases:** B-cell NHL (MESH:D016393), organizing pneumonia (MESH:D000092124), Pulmonary lymphoma (MESH:D008223), NHL (MESH:D008228), hepatic lesions (MESH:D056486), chronic gastritis (MESH:D005756), alopecia areata (MESH:D000506), dyspeptic symptoms (MESH:D012816), anemia (MESH:D000740), infection (MESH:D007239), loss of weight (MESH:D015431), MZL (MESH:D018442), cough (MESH:D003371), lesion (MESH:D009059), autoimmune (MESH:D001327), hair loss (MESH:D000505), chest pain (MESH:D002637), IDA (MESH:D018798), -cell B cell (MESH:D015448), fever (MESH:D005334), chronic inflammation (MESH:D007249), tumor (MESH:D009369), lung mass (MESH:D008171), lung malignancies (MESH:D008175), dyspnea (MESH:D004417)
- **Chemicals:** rituximab (MESH:D000069283), FDG (MESH:D019788)
- **Species:** Achromobacter xylosoxidans (species) [taxon 85698], Helicobacter pylori (species) [taxon 210], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12917332/full.md

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Source: https://tomesphere.com/paper/PMC12917332