# Analysis of root canal anatomy configuration in permanent anterior teeth among the Pakistani subpopulations using cone-beam CT

**Authors:** Mohmed Isaqali Karobari, Abdul Habeeb Adil, Azhar Iqbal, Hamza Arshad, Fatima Zahra, Fahad Umer, Irfan Maqbool, Venkata Suresh Venkataiah, Tahir Yusuf Noorani

PMC · DOI: 10.3389/froh.2026.1750120 · Frontiers in Oral Health · 2026-02-05

## TL;DR

This study analyzed root canal structures in front teeth of Pakistani people using CT scans, finding common patterns and differences by age and gender.

## Contribution

The study provides new regional data on root canal configurations in Pakistani populations, highlighting age and gender-related variations.

## Key findings

- The most common root canal configuration was single root with single canal (1TN1), found in 84.66% of cases.
- Age-related differences were observed in maxillary lateral incisors and mandibular canines.
- Females showed higher prevalence of specific root canal variants in certain teeth compared to males.

## Abstract

This study aimed to analyse root canal configurations in permanent maxillary and mandibular anterior teeth using cone-beam CT among a Pakistani subpopulation.

A total of 7,653 maxillary and mandibular anterior teeth were included from the retrospective analysis of 707 CBCT scans from two institutions. The CBCT images were visualized using GALAXIS integrated within the Sirona Dental System. The scanning parameters were standardized at 85 kV, 7 mA, with a 15-second exposure time and a voxel size of 0.16 mm. Statistical analyses were performed using SPSS version 26, employing the Chi-square test with a significance level set at p < 0.05.

The predominant root canal configuration observed across all maxillary and mandibular anterior teeth was single root with single canal (1TN1), comprising 84.66% of cases. Significant variations were noted in maxillary lateral incisors and mandibular canines across different age groups (p < 0.05), indicating age-related differences in root canal morphology in these teeth. Gender-based analysis revealed significant differences in root canal configurations for maxillary canines and mandibular central and lateral incisors (p < 0.05), with females exhibiting a higher prevalence of specific variants compared to males.

The study successfully identified the predominant root canal configurations in a Pakistani subpopulation, revealing significant age and gender-related differences. The predominance of the single root with single (1TN1) canal configuration underscores its clinical relevance and prevalence across different demographic factors. The findings emphasize the importance of demographic considerations in endodontic treatment planning, contributing valuable regional data to the field.

## Full-text entities

- **Diseases:** caries (MESH:D003731), fractures (MESH:D050723)
- **Species:** Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## Figures

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## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12916693/full.md

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Source: https://tomesphere.com/paper/PMC12916693