# Using serious games for cardiopulmonary resuscitation training: a meta-analysis and systematic review

**Authors:** Zongrong Chen, Ying Chen, Lu Zhang, Zhenhua He

PMC · DOI: 10.3389/fpubh.2026.1726862 · Frontiers in Public Health · 2026-02-05

## TL;DR

This study reviews whether serious games improve CPR training compared to traditional methods and finds no significant difference in outcomes.

## Contribution

A meta-analysis and systematic review of serious games for CPR training, revealing no significant advantage over traditional methods.

## Key findings

- No significant differences in CPR compression depth, rate, knowledge, or skill scores between serious games and traditional training.
- Significant publication bias detected in theoretical and skill scores.
- High heterogeneity across studies suggests caution in interpreting pooled results.

## Abstract

Serious games have emerged as an innovative educational approach, holding potential to improve the quality and efficacy of cardiopulmonary resuscitation (CPR) training. The objective of this meta-analysis was to systematically evaluate the impact of serious games on CPR training and educational outcomes.

We systematically searched eight databases to identify randomized controlled trials (RCTs) that compared the effectiveness of serious games with that of traditional training in CPR education. The literature search was conducted up to September 20, 2025. All statistical analyses were performed using RevMan 5.4 software.

A total of 11 RCTs involving 409 participants in the serious game groups and 388 participants in the control groups were included. We found no statistically significant differences between groups in CPR compression depth (SMD = 0.63, 95% CI: −0.09 to 1.35, p = 0.08), compression rate (SMD = –0.04, 95% CI: −0.53 to 0.44, p = 0.86), theoretical knowledge scores (SMD = –0.22, 95% CI: −0.96 to 0.51, p = 0.55), or practical skill scores (SMD = −0.18, 95% CI: −1.02 to 0.66, p = 0.67). Egger regression analysis indicated significant publication bias in theoretical scores (p = 0.015) and skill scores (p = 0.022) in this meta-analysis. The high heterogeneity observed across studies necessitates cautious interpretation of these pooled results.

Current evidence does not show a statistically significant advantage for serious games over traditional CPR training methods. Importantly, the evidence is also insufficient to confirm their true equivalence. A cautious stance regarding their widespread adoption is therefore warranted. Future research should prioritize high-quality, adequately powered studies with rigorous designs, standardized intervention protocols (e.g., game types, training duration), and unified internationally recognized assessment standards.

## Full-text entities

- **Diseases:** death (MESH:D003643), SCA (MESH:D016757), CPR (MESH:D006323)
- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12916568/full.md

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Source: https://tomesphere.com/paper/PMC12916568