# Associations of the triglyceride-glucose index, triglyceride glucose-body mass index, waist-triglyceride index and modified triglyceride-glucose indices with mortality in cardiovascular-kidney-metabolic syndrome stages 0–4: Evidence from NHANES 1999–2020

**Authors:** Jingya Zhao, Xinning Lu, Hui Wang, Qin Chen, Yigang Wan

PMC · DOI: 10.1515/jtim-2026-0014 · Journal of Translational Internal Medicine · 2026-02-13

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}, CKM (creatine kinase, M-type) [NCBI Gene 1158] {aka CKMM, CPK-M, M-CK}, INSR (insulin receptor) [NCBI Gene 3643] {aka CD220, HHF5}, VCAM1 (vascular cell adhesion molecule 1) [NCBI Gene 7412] {aka CD106, INCAM-100}, NOS3 (nitric oxide synthase 3) [NCBI Gene 4846] {aka EC-NOS, ECNOS, MYMY8, NOSIII, cNOS, eNOS}
- **Diseases:** CKD (MESH:D051436), DM (MESH:D003920), MetS (MESH:D024821), hyperglycemia (MESH:D006943), fibrosis (MESH:D005355), inflammation (MESH:D007249), sarcopenia (MESH:D055948), TyG (MESH:C566031), metabolic abnormalities (MESH:D008659), obesity (MESH:D009765), IR (MESH:D007333), CVD (MESH:D002318), uremic toxins (MESH:D006463), atherosclerosis (MESH:D050197), malnutrition (MESH:D044342), deaths (MESH:D003643), hypertension (MESH:D006973), thrombosis (MESH:D013927), , heart disease (MESH:D006331), CKM syndrome (MESH:D007674), heart failure (MESH:D006333)
- **Chemicals:** triglyceride (MESH:D014280), NO (MESH:D009569), thromboxane A2 (MESH:D013928), AGEs (MESH:D017127), TyG (-), glucose (MESH:D005947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12916274/full.md

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Source: https://tomesphere.com/paper/PMC12916274