# Treatment of a Type II Endoleak from an Atypical Mediastinal Collateral Branch Following Total Arch Replacement with Frozen Elephant Trunk

**Authors:** Emiko Chiba, Kohei Hamamoto, Mamoru Arakawa, Satoshi Uesugi, Soichiro Kojima, Ryoma Kobayashi, Tatsuya Ogawa, Hiroyuki Fujii, Mitsuru Matsuki, Harushi Mori

PMC · DOI: 10.3400/avd.cr.25-00124 · Annals of Vascular Diseases · 2026-02-17

## TL;DR

A rare case of a type II endoleak from an unusual mediastinal artery after aortic surgery was successfully treated with embolization.

## Contribution

Presents a novel case of atypical type II endoleak source following frozen elephant trunk surgery.

## Key findings

- A type II endoleak originated from a newly developed mediastinal collateral artery after FET.
- Selective embolization with N-butyl-2-cyanoacrylate effectively resolved the endoleak.
- Atypical T2EL sources should be considered in post-FET aneurysm expansion cases.

## Abstract

We present a rare case of type II endoleak (T2EL) from an atypical mediastinal artery following total arch replacement with a frozen elephant trunk (FET) for chronic aortic dissection. A 63-year-old male with a history of multiple thoracic aortic surgeries, including FET, developed enlargement of an aortic arch aneurysm on follow-up. Computed tomography and diagnostic angiography revealed a T2EL due to a newly developed mediastinal collateral artery arising from the left subclavian artery feeding the sac. Selective transcatheter embolization with N-butyl-2-cyanoacrylate successfully eliminated the endoleak. Recognizing such atypical T2EL sources is crucial for managing post-FET aneurysm expansion.

## Linked entities

- **Chemicals:** N-butyl-2-cyanoacrylate (PubChem CID 23087)

## Full-text entities

- **Diseases:** subclavian artery obstruction (MESH:D013349), TAE (MESH:D004617), hypertension (MESH:D006973), aortic arch aneurysm (MESH:D000094626), cerebral infarction (MESH:D002544), paralysis (MESH:D010243), DeBakey type I (MESH:D006969), hyperlipidemia (MESH:D006949), thoracic aortic aneurysm (MESH:D017545), cystic fibrosis (MESH:D003550), Type II Endoleak (MESH:D057867), aneurysm (MESH:D000783), aortic dissection (MESH:D000784), rupture (MESH:D012421), aortic coarctation (MESH:D001017)
- **Chemicals:** warfarin (MESH:D014859), EC (-), Lipiodol (MESH:D004998), N-butyl-2-cyanoacrylate (MESH:D004659)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12916235/full.md

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Source: https://tomesphere.com/paper/PMC12916235