# Unilateral Pseudo–Double Side-by-Side Lined Macular Neovascularizations in Pathologic Myopia

**Authors:** Eda Hümaz, Seher Köksaldı, Mustafa Kayabaşı, Ali Osman Saatci

PMC · DOI: 10.7759/cureus.101837 · Cureus · 2026-01-19

## TL;DR

A rare case of complex macular neovascularization in a patient with pathologic myopia is described, emphasizing the importance of advanced imaging for accurate diagnosis and treatment.

## Contribution

The case presents a pseudo-double macular neovascularization configuration, highlighting the role of OCTA in identifying anatomical connections.

## Key findings

- Multimodal imaging revealed two side-by-side macular neovascularizations with anatomical continuity.
- OCTA confirmed the pseudo-double configuration and guided treatment with ranibizumab injections.
- The case underscores the need for advanced imaging in diagnosing complex MNV in pathologic myopia.

## Abstract

Pathologic myopia may be complicated by macular neovascularization (MNV) with atypical morphological configurations that can be challenging to characterize without multimodal imaging. A 50-year-old woman with pathologic myopia was examined due to a two-week history of newly developed left visual deterioration. Upon ophthalmological examination, her best-corrected Snellen visual acuity was hand motion in the right eye and 6/15 in the left eye. Slit-lamp examination revealed +4 nuclear sclerosis in the right eye, whereas the left eye appeared normal. Axial length measured by A-mode ultrasonography was 30.55 in the right eye and 28.04 in the left eye. The right fundus could be visualized only with indirect ophthalmoscopy, and there was severe patchy atrophy. There were two hyperpigmented side-by-side lined lesions indicating the presence of two macular neovascularizations at the left macula. Subfoveal spectral-domain optical coherence tomographic section depicted two hyperreflective materials located side by side at the outer retina, accompanied by mild intraretinal fluid. Optical coherence tomography angiography (OCTA) confirmed the presence of the pseudo-double MNV with an anatomical connection. The only good newly symptomatic left eye was treated with two intravitreal ranibizumab injections one month apart. The present case highlights that MNV associated with pathologic myopia may present with complex, pseudo-double configurations that can be accurately identified only through multimodal imaging. OCTA plays a crucial role in delineating the anatomical continuity and morphological characteristics of such lesions, thereby contributing to accurate diagnosis, treatment planning, and prognostic assessment.

## Full-text entities

- **Genes:** VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}
- **Diseases:** intraretinal cyst (MESH:D003560), MNV lesions (MESH:D009389), visual deterioration (MESH:C531604), choroidal thinning (MESH:D013851), cataract (MESH:D002386), infective endocarditis (MESH:D004696), hypoxic (MESH:D002534), posterior staphyloma (MESH:C536352), hemorrhage (MESH:D006470), Pathologic Myopia (MESH:D047728), Myopic MNV (MESH:D001251), exudative lesion (MESH:D011504), MNV (MESH:D008268), chorioretinal involvement (MESH:D002825), atrophy (MESH:D001284), myopia (MESH:D009216), exudative vitreoretinopathy (MESH:D000080345), scotoma (MESH:D012607), ocular tuberculosis (MESH:D014392), intraretinal (MESH:D006949), melanoma (MESH:D008545), vision loss (MESH:D014786), nuclear sclerosis (MESH:C563333), chorioretinal atrophy (MESH:C566236)
- **Chemicals:** ipilimumab (MESH:D000074324), fluorescein (MESH:D019793), ranibizumab (MESH:D000069579), indocyanine green (MESH:D007208)
- **Species:** Staphylococcus aureus (species) [taxon 1280], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12915064/full.md

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Source: https://tomesphere.com/paper/PMC12915064