# Unraveling the enigma of eosinophilic gastroenteritis: a rare case of multisystem involvement in an elderly patient

## TL;DR

A rare case of eosinophilic gastroenteritis in an elderly man is described, emphasizing the need for early diagnosis and treatment.

## Contribution

This case report highlights the multisystem involvement of EG in an elderly patient and underscores diagnostic challenges.

## Key findings

- EG was diagnosed in a 77-year-old male with chest pain, weight loss, and eosinophilia.
- Prednisone treatment led to significant clinical improvement.
- EG should be considered in patients with unexplained gastrointestinal symptoms and eosinophilia.

## Abstract

Eosinophilic gastroenteritis (EG), the most common form of eosinophilic gastrointestinal disease, primarily affects the stomach and small intestine. This retrospective case report, following CARE guidelines, analyzed clinical data and imaging. A 77-year-old male presented with substernal chest pain, weakness, appetite loss, and weight loss. CBC showed leukocytosis with marked eosinophilia. Abdominal CT revealed thickened jejunal loops. Biopsies confirmed eosinophilic infiltration in the duodenum and ileum, diagnosing EG. The patient was treated with prednisone, leading to significant improvement. This case highlights the importance of recognizing EG in patients with unexplained GI symptoms and eosinophilia for timely diagnosis and effective management.