# Dynamic ST-Segment Elevation in Massive Pulmonary Embolism Captured by Holter Electrocardiography: A Case Report

**Authors:** Ko Nagai, Taichi Kato, Seiji Domae, Kazuhiro Sugiyama

PMC · DOI: 10.7759/cureus.101815 · Cureus · 2026-01-18

## TL;DR

A case report shows that ST-segment elevation after cardiac arrest can be caused by massive pulmonary embolism, not just heart attack, highlighting the need for careful diagnosis.

## Contribution

This case highlights the dynamic nature of ECG changes in PE and emphasizes the importance of echocardiography in accurate diagnosis.

## Key findings

- ST-segment elevation after cardiac arrest was linked to massive pulmonary embolism, not coronary occlusion.
- Holter monitoring captured dynamic ECG changes, showing elevation after cardiac arrest and gradual resolution.
- Echocardiography revealed right ventricular dilation, supporting the diagnosis of PE.

## Abstract

ST-segment elevation on a post-cardiac arrest electrocardiogram (ECG) is traditionally viewed as a hallmark of acute coronary occlusion. However, this finding can also arise from non-coronary etiologies like massive pulmonary embolism (PE), creating a high-stakes diagnostic dilemma. An 83-year-old woman hospitalized for trauma developed cardiac arrest with pulseless electrical activity (PEA). Immediate post-resuscitation ECG showed marked ST-segment elevation in leads V1-V4, II, III, and aVF, suggesting extensive myocardial infarction. A point-of-care echocardiogram showed severe right ventricular dilation, raising the suspicion of PE, which was confirmed by computed tomography. Fortuitously, a Holter monitor was attached, capturing the sequence of ECG changes before and after the onset of PE. It revealed that ST-segment elevation appeared after the onset of cardiac arrest and gradually decreased thereafter. The patient was successfully treated with anticoagulation. This case suggests that post-arrest ST-segment elevation in PE may reflect dynamic right ventricular strain and supply-demand mismatch, rather than fixed coronary occlusion. Recognizing the "dynamic" nature of these ECG changes, alongside rapid echocardiographic assessment, is essential to avoid unnecessary emergent coronary angiography and ensure timely treatment for PE.

## Linked entities

- **Diseases:** pulmonary embolism (MONDO:0005279), cardiac arrest (MONDO:0000745), myocardial infarction (MONDO:0005068)

## Full-text entities

- **Diseases:** hematoma (MESH:D006406), thrombus (MESH:D013927), trauma (MESH:D014947), coronary lesions (MESH:D003327), ACS (MESH:D054058), PEA (MESH:D013625), head trauma (MESH:D006259), hypertension (MESH:D006973), fractures (MESH:D050723), aortic dissection (MESH:D000784), RBBB (MESH:D002037), plaque rupture (MESH:D012421), myocardial ischemia (MESH:D017202), motion (MESH:D009041), acute myocardial infarction (MESH:D009203), right ventricular enlargement (MESH:D018497), coronary artery occlusion (MESH:D054059), chest compressions (MESH:D013898), arrest (MESH:D006323), bleeding (MESH:D006470), ST-segment elevation myocardial infarction (MESH:D000072657), intracranial hemorrhage (MESH:D020300), left ventricular perfusion defects (MESH:D018487), RV dilation (MESH:C566255), coronary embolisms (MESH:D004617), paradoxical embolism (MESH:D019320), cardiac ischemic (MESH:D006331), RV strain (MESH:D013180), coronary artery disease (MESH:D003324), ROSC (MESH:D005598), chest pain (MESH:D002637), PE (MESH:D011655), Emboli (MESH:D020766), single-vessel occlusion (MESH:D012640), ischemia (MESH:D007511), coronary artery stenosis (MESH:D023921), Coma (MESH:D003128)
- **Chemicals:** epinephrine (MESH:D004837), heparin (MESH:D006493)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12914609/full.md

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12914609/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12914609/full.md

---
Source: https://tomesphere.com/paper/PMC12914609