# Cries, Stridor, and Clues: Unmasking a Rare Airway Obstruction in an Infant

**Authors:** Karthikeyan V P, Dharshana R, Hariprasad R, Senthil Kumar K, Senguttuvan D, Hari Meyyappan

PMC · DOI: 10.7759/cureus.101842 · Cureus · 2026-01-19

## TL;DR

This paper presents a rare case of a vallecular cyst in an infant causing breathing issues, highlighting the importance of accurate diagnosis and treatment.

## Contribution

The novelty lies in documenting a rare case of vallecular cyst in infants and advocating complete excision over other treatments.

## Key findings

- Vallecular cysts are rare but should be considered in infants with stridor and respiratory distress.
- Complete excision of the cyst effectively resolved symptoms and prevented recurrence.
- Thorough clinical evaluation and interdisciplinary collaboration are crucial for accurate diagnosis.

## Abstract

Laryngomalacia is the predominant cause of airway obstruction resulting in stridor among newborns, constituting a significant percentage of all congenital stridor instances. Vallecular cysts, though rare, represent an important differential diagnosis, responsible for a notable percentage of all congenital laryngeal cysts. The frequency of vallecular cysts is considered low among newborns. We report a vallecular cyst case in a baby who had respiratory distress and inspiratory stridor. Diagnosis was made by direct laryngoscopy, and the cyst was completely excised, resulting in the resolution of symptoms. On follow-up after a few months, there was no evidence of recurrence. This case is documented due to its rarity and to enhance awareness of vallecular cysts as a possible etiology of stridor and respiratory distress in babies. It also emphasizes the importance of thorough clinical assessment and interdisciplinary evaluation. Furthermore, the case highlights the effectiveness of complete excision over marsupialization in preventing recurrence.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** craniofacial abnormalities (MESH:D019465), lingual (MESH:D046151), micrognathia (MESH:D008844), epiglottic cyst (MESH:D004826), noisy breathing (MESH:D004417), saccular cyst (MESH:D000783), infection (MESH:D007239), Cystic mass (MESH:D018297), choanal atresia (MESH:D002754), Laryngomalacia (MESH:D055092), macroglossia (MESH:D008260), lymphatic malformation (MESH:D008209), dysmorphism (MESH:D057215), failure to thrive (MESH:D005183), congenital laryngeal cysts (MESH:D007827), tracheal stenosis (MESH:D014135), mucous retention cyst (MESH:D016055), congenital malformations (OMIM:163000), congenital stridor (MESH:C563163), tracheomalacia (MESH:D055090), respiratory infection (MESH:D012141), congenital anomalies (MESH:D000013), congenital airway anomalies (MESH:C565562), bronchogenic cysts (MESH:D001994), Aryepiglottic cysts (MESH:D003560), laryngeal clefts (MESH:C537875), Airway Obstruction (MESH:D000402), vocal cord paralysis (MESH:D014826), malformations (MESH:C564254), hemangioma (MESH:D006391), base-of-the-tongue cyst (MESH:D014060), Respiratory distress (MESH:D012128), subglottic stenosis (MESH:D007829), tracheobronchomalacia (MESH:D055089), Feeding difficulty (MESH:D001068), respiratory compromise (MESH:D012131), structural abnormalities (MESH:C566527), thyroglossal cyst (MESH:D013955), ductal cyst (MESH:D044584), hoarse cry (MESH:D006685), Stridor (MESH:D012135), congenital structural abnormalities (MESH:D020914)
- **Chemicals:** HCO3 (MESH:D001639), ammonia (MESH:D000641), O2 (MESH:D010100), pCO2 (-), PO2 (MESH:C093415), CO2 (MESH:D002245)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12914589/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12914589/full.md

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Source: https://tomesphere.com/paper/PMC12914589