# Simultaneous Resection for Type A Thymoma With Synchronous Solitary Pulmonary Metastasis: A Case Report

**Authors:** Takamitsu Hayakawa, Mikako Mitake, Hirohisa Inaba, Saita Miyamoto, Takuya Masuda, Shingo Takahashi, Atsuki Fukada, Ai Sugimoto, Masako Morita, Hiroyuki Matsuda, Asako Okabe, Kazuhito Funai

PMC · DOI: 10.1002/rcr2.70512 · Respirology Case Reports · 2026-02-18

## TL;DR

A patient with a rare thymoma type had a lung metastasis removed at the same time as the primary tumor, showing that even small, low-grade thymomas can spread and may benefit from combined surgery.

## Contribution

This case report presents a rare instance of simultaneous resection for type A thymoma with a solitary pulmonary metastasis.

## Key findings

- A patient with a 2.0 cm mediastinal nodule and a 0.9 cm pulmonary nodule had both resected via video-assisted thoracoscopic surgery.
- Histopathology confirmed type A thymoma with solitary pulmonary metastasis, with no recurrence after 1 year.
- The case suggests simultaneous resection can be effective for small, low-grade type A thymoma with metastasis.

## Abstract

Type A thymoma is associated with an excellent prognosis, and distant metastasis is uncommon. Optimal management for metastatic type A thymoma has not been well documented. We report a case of conventional type A thymoma with synchronous solitary pulmonary metastasis treated with simultaneous resection. An 81‐year‐old woman was incidentally found to have both a 2.0 cm anterior mediastinal nodule and a 0.9 cm pulmonary nodule in the left lower lobe. Both lesions were resected via video‐assisted thoracoscopic surgery. Histopathology and immunohistochemistry revealed identical features in both tumours, confirming type A thymoma with solitary pulmonary metastasis (pT1aN0M1b, stage IVb). No histopathological features of atypical type A thymoma were present. The patient remains recurrence‐free 1 year after surgery without adjuvant therapy. This case suggests that pulmonary metastasis can occur even in small, low‐grade type A thymoma and that simultaneous resection for diagnostic and therapeutic purposes may be considered to achieve favourable outcomes.

We report a case of conventional type A thymoma with synchronous solitary pulmonary metastasis treated with simultaneous resection. This case suggests that pulmonary metastasis can occur even in small and low‐grade type A thymoma. Simultaneous resection for diagnostic and therapeutic purposes may be considered to achieve favourable outcomes.

## Full-text entities

- **Genes:** TENM1 (teneurin transmembrane protein 1) [NCBI Gene 10178] {aka ODZ1, ODZ3, TEN-M1, TEN1, TNM, TNM1}, GATA3 (GATA binding protein 3) [NCBI Gene 2625] {aka HDR, HDRS}, CD99 (CD99 molecule (Xg blood group)) [NCBI Gene 4267] {aka HBA71, MIC2, MIC2X, MIC2Y, MSK5X}, IL9 (interleukin 9) [NCBI Gene 3578] {aka HP40, IL-9, P40}
- **Diseases:** anterior mediastinal tumour (MESH:D008479), thymic epithelial tumours (MESH:C536905), pulmonary (MESH:D008171), benign tumour (MESH:D009369), IVb (MESH:D009085), breast cancer (MESH:D001943), anterior mediastinal lesion (MESH:D008477), A thymoma (MESH:D013945), necrosis (MESH:D009336), Pulmonary Metastasis (MESH:D009362)
- **Chemicals:** haematoxylin (MESH:D006416)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12914481/full.md

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Source: https://tomesphere.com/paper/PMC12914481