# Successful transcatheter pulmonary valve implantation under elective extracorporeal membrane oxygenation in a patient with tetralogy of Fallot with biventricular failure and ventricular tachycardia: a case report

**Authors:** Hidehiro Mori, Mizuhiko Ishigaki, Sung-Hae Kim, Akane Shibuya, Yasuhiko Tanaka

PMC · DOI: 10.1093/ehjcr/ytag044 · European Heart Journal. Case Reports · 2026-01-29

## TL;DR

A high-risk patient with complex heart disease successfully underwent a valve implantation procedure with the help of a special life-support system.

## Contribution

This case report demonstrates the safe use of elective ECMO support during transcatheter pulmonary valve implantation in a high-risk patient.

## Key findings

- Elective ECMO provided stable hemodynamics during TPVI in a patient with biventricular failure and arrhythmias.
- The patient had no complications and was discharged six days after the procedure.
- This approach may be a viable option for high-risk patients with pulmonary valve dysfunction.

## Abstract

We report a case of successful transcatheter pulmonary valve implantation (TPVI) with elective extracorporeal membrane oxygenation (ECMO) support in a high-risk patient with complex congenital heart disease complicated by severe biventricular heart failure and ventricular tachycardia (VT).

A 55-year-old woman with a history of tetralogy of Fallot underwent surgical repair at the age of 3 years. At 50 years of age, the patient underwent bioprosthetic pulmonary valve replacement because of severe pulmonary regurgitation. Two years later, valve thrombosis required valve replacement, followed by infective endocarditis, leading to progressive pulmonary valve stenosis and regurgitation. This results in right ventricular dilation, biventricular failure, and recurrent VT. Given its high surgical risk, TPVI was selected. Owing to the impaired cardiac function and arrhythmia risk, elective ECMO support was planned to prevent intraoperative haemodynamic collapse. On the day of the procedure, ECMO was initiated in the hybrid OR, and TPVI was successfully performed using a 26 mm SAPIEN 3 valve. ECMO provided stable haemodynamics throughout the procedure, and the patient was successfully weaned postoperatively in the hybrid room. The patient had no complications and was discharged on postoperative Day 6.

Reports on TPVI with elective ECMO support are limited. This case suggests that in high-risk patients with severe heart failure and arrhythmias due to pulmonary valve dysfunction, elective ECMO can provide haemodynamic stability and allow TPVI to be safely performed with favourable outcomes.

## Linked entities

- **Diseases:** tetralogy of Fallot (MONDO:0008542), ventricular tachycardia (MONDO:0005477), pulmonary regurgitation (MONDO:0001927), infective endocarditis (MONDO:0000565)

## Full-text entities

- **Genes:** NPPB (natriuretic peptide B) [NCBI Gene 4879] {aka BNP, Iso-ANP}
- **Diseases:** haemodynamic collapse (MESH:D001261), pulmonary artery stenosis (MESH:D000071079), cardiac arrest (MESH:D006323), diastolic murmur (MESH:D006337), congenital heart disease (MESH:D006330), biventricular dysfunction (MESH:D018754), biventricular failure (MESH:D051437), right ventricular pressure and volume overload (MESH:D018497), pulmonary valve dysfunction (MESH:D006349), decreased cardiac output (MESH:D002303), cardiomegaly (MESH:D006332), impaired cardiac function (MESH:D006331), right ventricular dilation (MESH:C566255), mediastinitis (MESH:D008480), arrhythmia (MESH:D001145), biventricular heart failure (MESH:D006333), renal dysfunction (MESH:D007674), infective endocarditis (MESH:D004696), systolic murmur (MESH:D054160), PS (MESH:D011666), regurgitation (MESH:D008944), heartbeats (MESH:D005117), PR (MESH:D011665), TOF (MESH:D013771), PVCs (MESH:D018879), coronary (MESH:D003323), VT (MESH:D017180)
- **Chemicals:** Levine (-), Catecholamine (MESH:D002395), amiodarone (MESH:D000638), Creatinine (MESH:D003404)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12914463/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12914463/full.md

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Source: https://tomesphere.com/paper/PMC12914463