# HepAssis2® bioartificial liver system in treating acute‐on‐chronic liver failure patients: Findings from a phase 1 randomised, open‐label clinical trial

**Authors:** Zibiao Zhong, Wenjin Liang, Yong'an Dai, Chengbiao Xue, Dawei Zhou, Zhigao Xu, Ling Li, Li Pan, Chongxiang He, Xin Zhou, Wei Zhou, Lihua Zhou, Zhongzhong Liu, Zhiping Xia, Xiaoli Fan, Guizhu Peng, Yanfeng Wang, Ping Zhou, Shaojun Ye, Qifa Ye

PMC · DOI: 10.1002/ctm2.70620 · Clinical and Translational Medicine · 2026-02-18

## Full-text entities

- **Diseases:** sepsis (MESH:D018805), cerebral herniation (MESH:D004677), hepatic disease (MESH:D056486), liver failure (MESH:D017093), allergic reactions (MESH:D004342), respiratory failure (MESH:D012131), embolic phenomena (MESH:D004617), infections (MESH:D007239), chills (MESH:D023341), MELD (MESH:D058625), ACLF (MESH:D065290)
- **Chemicals:** methylprednisolone (MESH:D008775), bilirubin (MESH:D001663), DPMAS (MESH:C056426), HepAssis2 (-)
- **Species:** Hepatitis B virus (no rank) [taxon 10407], Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** L-02 — Homo sapiens (Human), Human papillomavirus-related endocervical adenocarcinoma, Cancer cell line (CVCL_6926)

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12914335/full.md

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Source: https://tomesphere.com/paper/PMC12914335