# From Animals to Arthroplasty: Insights From Three Cases of Pasteurella Prosthetic Joint Infection and a Comprehensive Review of the Literature

**Authors:** Wankumbu Chisala, Matthew Saunders, Robert Townsend, David Partridge

PMC · DOI: 10.1155/cris/4246149 · Case Reports in Surgery · 2026-02-18

## TL;DR

This paper reports three cases of joint infections caused by Pasteurella bacteria after animal contact and highlights the risks for people who have had joint replacements.

## Contribution

The study adds three new clinical cases and provides a comprehensive review of Pasteurella prosthetic joint infections.

## Key findings

- Pasteurella infections after animal contact are rare but serious for joint replacement patients.
- Most infections occurred after scratches, bites, or licks from cats and dogs.
- Patients often underestimate the risk of infection from minor animal injuries.

## Abstract

Pasteurella spp. are rare but important zoonotic pathogens that can cause prosthetic joint infection (PJI). We present 3 cases of Pasteurella prosthetic joint infections (PJIs) following close animal contact that required treatment with DAIR (debridement, antibiotics, and implant retention) procedures. An extensive literature review was performed which identified 57 described cases of PJI. Transmission commonly occurred following scratches, bites and licks from cats and dogs. Patients often do not recognise the potential severity of these injuries and should be warned following arthroplasty of the risks of infection due to Pasteurella spp. following close contact with these animals, particularly given the increased morbidity and mortality associated with PJI.

## Linked entities

- **Diseases:** Pasteurella infection (MONDO:0005901)

## Full-text entities

- **Genes:** CD8A (CD8 subunit alpha) [NCBI Gene 925] {aka CD8, CD8alpha, IMD116, Leu2, p32}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** joint swelling (MESH:D007592), Infection (MESH:D007239), factor XI deficiency (MESH:D005173), death (MESH:D003643), stiffness (MESH:C566112), psychotic depression (MESH:D000341), Pasteurella disease (MESH:D010326), rheumatoid arthritis (MESH:D001172), lethargic (MESH:D004674), diverticular abscess (MESH:D000076385), infectious (MESH:D003141), bloodstream infections (MESH:D018805), insect bite (MESH:D007299), septic arthritis (MESH:D001170), erythema (MESH:D004890), cellulitis (MESH:D002481), endocarditis (MESH:D004696), chronic pain (MESH:D059350), swelling (MESH:D004487), meningitis (MESH:D008580), shoulder infections (MESH:D020069), pain (MESH:D010146), gout (MESH:D006073), SSTI (MESH:D018461), injuries (MESH:D014947), periprosthetic joint infection (MESH:D057068), penicillin allergy (MESH:D008586), osteoarthritis (MESH:D010003), deficit (MESH:D009461), pneumonia (MESH:D011014), knee pain (MESH:D046788), rash (MESH:D005076), staphylococcal (MESH:D011023)
- **Chemicals:** Fluoroquinolones (MESH:D024841), cephalosporins (MESH:D002511), aztreonam (MESH:D001398), cefuroxime (MESH:D002444), penicillins (MESH:D010406), Hartmann (-), flucloxacillin (MESH:D005436), ampicillin (MESH:D000667), ciprofloxacin (MESH:D002939), metronidazole (MESH:D008795), amoxicillin-clavulanic acid (MESH:D019980), piperacillin (MESH:D010878), teicoplanin (MESH:D017334), doxycycline (MESH:D004318), tazobactam (MESH:D000078142), benzylpenicillin (MESH:D010400)
- **Species:** [Pasteurella] aerogenes (species) [taxon 749], Homo sapiens (human, species) [taxon 9606], Felis catus (cat, species) [taxon 9685], Staphylococcus (genus) [taxon 1279], Pasteurella dagmatis (species) [taxon 754], Pasteurella stomatis (species) [taxon 760], Equus caballus (domestic horse, species) [taxon 9796], Pasteurella multocida (species) [taxon 747], Canis lupus familiaris (dog, subspecies) [taxon 9615], Pasteurella canis (species) [taxon 753]
- **Mutations:** F

## Full text

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## References

71 references — full list in the complete paper: https://tomesphere.com/paper/PMC12914333/full.md

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Source: https://tomesphere.com/paper/PMC12914333