# Multiple Granular Cell Tumors of the New Born: A Case Report and Literature Review **Authors:** Fawzia M. Butt, Shamim A. Butt, M. L. Chindia PMC · DOI: 10.1002/ccr3.72034 · Clinical Case Reports · 2026-02-17 ## TL;DR A newborn had multiple benign oral tumors that were surgically removed, leading to a full recovery. ## Contribution This case report adds to the limited literature on congenital granular cell epulis in newborns. ## Key findings - The tumors were confined intra-orally and did not spread. - Surgical excision led to smooth recovery and excellent prognosis. - The case highlights the rarity and clinical management of this condition in newborns. ## Abstract Congenital granular cell epulis, a rare benign tumor, predominant in females present on the maxillary alveolar ridge. A newborn exhibited multiple oral tumors, interfering with breastfeeding. CT scan showed its confinement intra‐orally. The tumors were excised and surgical site closed primarily. Recovery was smooth with excellent prognosis. Preoperative clinical photo highlighting the intra oral maxillary masses. ## Full-text entities - **Genes:** PECAM1 (platelet and endothelial cell adhesion molecule 1) [NCBI Gene 5175] {aka CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM}, VIM (vimentin) [NCBI Gene 7431], CALB2 (calbindin 2) [NCBI Gene 794] {aka CAB29, CAL2, CR}, ENO2 (enolase 2) [NCBI Gene 2026] {aka HEL-S-279, NSE}, CD68 (CD68 molecule) [NCBI Gene 968] {aka GP110, LAMP4, SCARD1}, CD34 (CD34 molecule) [NCBI Gene 947], SMN1 (survival of motor neuron 1, telomeric) [NCBI Gene 6606] {aka BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3}, S100A1 (S100 calcium binding protein A1) [NCBI Gene 6271] {aka S100, S100-alpha, S100A}, TNFRSF1B (TNF receptor superfamily member 1B) [NCBI Gene 7133] {aka CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B}, CMPK1 (cytidine/uridine monophosphate kinase 1) [NCBI Gene 51727] {aka CK, CMK, CMPK, UMK, UMP-CMPK, UMPK}, SLC2A1 (solute carrier family 2 member 1) [NCBI Gene 6513] {aka CSE, DYT17, DYT18, DYT9, EIG12, GLUT}, DES (desmin) [NCBI Gene 1674] {aka CDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R}, NGFR (nerve growth factor receptor) [NCBI Gene 4804] {aka CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR} - **Diseases:** congenital anomalies (MESH:D000013), Neumann tumor (MESH:C580150), Tumor (MESH:D009369), granular cell lesion (MESH:D000230), swelling (MESH:D004487), dental abnormalities (MESH:D014071), lip incompetence (MESH:D008047), CGCE (MESH:D005887), genetic defects (MESH:D030342), CGCE tumors (MESH:D016586), neuroectodermal tumor (MESH:D017599), melanotic (MESH:D018327), granular cell fibroblastoma (MESH:D018223), Abrikosov tumor (MESH:C535558), midface hypoplasia (MESH:C564570), infantile myofibroma (MESH:D047708), cleft of the palate (MESH:D002972), teratoma (MESH:D013724), maxillary masses (MESH:D008439), neonatal lesion (MESH:D007232), deformities (MESH:D009140), necrosis (MESH:D009336), hypoplastic tooth (MESH:D014076) - **Chemicals:** adrenaline (MESH:D004837), lignocaine (MESH:D008012), Hematoxylin (MESH:D006416), Eosin (MESH:D004801) - **Species:** Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12913699/full.md ## Figures 5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12913699/full.md ## References 14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12913699/full.md --- Source: https://tomesphere.com/paper/PMC12913699