# Influence of crystallization and adhesive cementation on the fracture resistance of CAD/CAM advanced lithium disilicate and zirconia-reinforced lithium silicate ceramics after thermocycling

**Authors:** Andrea Ordóñez Balladares, Luis Chauca-Bajaña, Marcela Alejandra Ordoñez Balladares, Rolando Fabricio Dau Villafuerte, Carlos Carpio-Cevallos, César Humberto Palacios Jurado, Elizabeth Cecilia Ortíz Matías, Gina Vasquez Armas, Juan Suarez-Palacios, Byron Velásquez Ron

PMC · DOI: 10.3389/fdmed.2026.1715080 · Frontiers in Dental Medicine · 2026-02-04

## TL;DR

This study examines how crystallization and adhesive cementation affect the fracture resistance of dental ceramics after thermal aging.

## Contribution

The study reveals a synergistic effect of crystallization and adhesive cementation on improving the mechanical performance of CAD/CAM ceramics.

## Key findings

- Crystallization and adhesive cementation significantly increased fracture resistance in tested ceramics.
- Tessera™ crystallized-cemented crowns showed the highest fracture resistance (1,918.9 ± 246.3 N).
- Thermocycling combined with proper protocols is essential for optimizing long-term performance.

## Abstract

Advancements in CAD/CAM glass-ceramics have expanded their use in esthetic dentistry; however, the combined influence of thermal processing and adhesive cementation on their mechanical performance after oral aging remains unclear.

To assess the effect of crystallization and adhesive cementation on the fracture resistance of CAD/CAM advanced lithium disilicate and zirconia-reinforced lithium silicate ceramics following thermocycling.

Eighty monolithic crowns (n = 10/group) were milled from advanced lithium disilicate (CEREC Tessera™), lithium disilicate (e.max CAD), and zirconia-reinforced lithium silicate (Vita Suprinity®). Specimens were assigned to eight groups based on crystallization and cementation protocols. All crowns underwent 5,000 thermocycles (5 °C–55 °C). Fracture resistance was measured under static compressive loading. Non-parametric tests (Kruskal–Wallis and Mann–Whitney U with Bonferroni correction) were applied (α = 0.05).

Both crystallization and adhesive cementation significantly increased fracture resistance (p < 0.05). Crystallized-cemented specimens exhibited the highest values across all materials. Tessera™ crystallized-cemented crowns reached the highest mean fracture resistance (1,918.9 ± 246.3 N), outperforming e.max CAD and Vita Suprinity®.

Crystallization and adhesive cementation exert synergistic benefits on the fracture resistance of CAD/CAM glass-ceramic crowns after thermocycling. Adhering to recommended thermal cycles and adhesive protocols is essential to optimize mechanical reliability and long-term performance.

## Full-text entities

- **Diseases:** fatigue (MESH:D005221), CAM (MESH:D020786), Fracture (MESH:D050723)
- **Chemicals:** isopropyl alcohol (MESH:D019840), CAD (MESH:C075764), polyethylene (MESH:D020959), water (MESH:D014867), Silane (MESH:D012821), HF (MESH:D006195), Zirconia (MESH:C028541), Hydrofluoric acid (MESH:D006858), CC (-), CNC (MESH:D000069449), stainless-steel (MESH:D013193)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** C-55  C, S 30 H

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12913558/full.md

## References

73 references — full list in the complete paper: https://tomesphere.com/paper/PMC12913558/full.md

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Source: https://tomesphere.com/paper/PMC12913558