# Knowledge, attitude, and practice of physicians toward the management of diabetic ketoacidosis

**Authors:** Mabrouk AL-Rasheedi, Baharudin Ibrahim, Khawaja Husnain Haider, Ahmed Amin Ali, Hadzliana Zainal

PMC · DOI: 10.3389/fcdhc.2026.1723632 · Frontiers in Clinical Diabetes and Healthcare · 2026-02-04

## TL;DR

This study assesses Saudi physicians' knowledge, attitudes, and practices in managing diabetic ketoacidosis, finding significant gaps that suggest a need for better training.

## Contribution

The study identifies demographic and professional factors influencing DKA management knowledge and highlights the need for targeted educational programs.

## Key findings

- Only 4.1% of physicians demonstrated good knowledge of DKA management protocols.
- Endocrinologists and older physicians showed significantly higher knowledge scores.
- Targeted educational interventions are needed to improve DKA management practices.

## Abstract

Diabetic ketoacidosis (DKA) is a serious complication of uncontrolled diabetes that results from insufficient insulin, high blood sugar levels, dehydration, and disturbances in acid-base status in the blood. This condition can arise from infections or treatment errors, such as inadequate insulin dosing or missed doses, and affects both type 1 and type 2 diabetes.

The study aims to identify gaps in physicians’ knowledge, attitudes, and practices (KAP) regarding the updated Diabetic Ketoacidosis protocol from the Ministry of Health (MoH) to enhance educational programs and improve patient outcomes.

This cross-sectional study, conducted between July 2023 and July 2024, involved 242 physicians treating DKA across ten tertiary hospitals in five administrative regions of Saudi Arabia. Interns and physicians with less than one year of experience were excluded. Data were collected using a validated KAP questionnaire.

Among the 242 physicians surveyed, 57.9% demonstrated poor knowledge, 38.0% had fair knowledge, and only 4.1% exhibited good knowledge (Mean ± SD: 4.79 ± 1.85). Knowledge levels were significantly higher among females (p=0.001), physicians over 40 years of age (p<0.001), those with more than 15 years of experience (p<0.001), and endocrinologists (Mean ± SD: 6.25 ± 1.26, p<0.001). A favorable attitude was observed in 68.6% of physicians (Mean ± SD: 8.03 ± 1.81), significantly influenced by marital status (p=0.002). Good practices were noted in 51.7% of the physicians (Mean ± SD: 3.05 ± 1.84), with significant predictors including age, gender, experience, and region (p<0.05). The overall model explained 34.5% of the variability in knowledge, 16% of the variability in attitude, and 30.2% of the variability in practice.

This study highlights significant gaps in physicians’ knowledge, attitudes, and practices regarding DKA management in Saudi Arabia. Younger, less experienced doctors tend to have lower knowledge scores, while higher scores are observed among endocrinologists and intensive care unit physicians, underscoring the need for targeted educational interventions.

## Linked entities

- **Diseases:** diabetic ketoacidosis (MONDO:0012819)

## Full-text entities

- **Genes:** GCG (glucagon) [NCBI Gene 2641] {aka GLP-1, GLP1, GLP2, GRPP}, INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** diabetic complications (MESH:D048909), inflammatory diseases (MESH:D007249), DM (MESH:D009223), pancreatitis (MESH:D010195), metabolic acidosis (MESH:D000138), absolute insulin deficiency (MESH:D007333), polydipsia (MESH:D059606), dehydration (MESH:D003681), Abdominal pain (MESH:D015746), Diabetes (MESH:D003920), insufficient (MESH:D000309), impaired (MESH:D060825), substance abuse (MESH:D019966), Infections (MESH:D007239), Type 1 Diabetes Mellitus (MESH:D003922), DKA (MESH:D016883), heart problems (MESH:D006331), nausea (MESH:D009325), Type 2 Diabetes Mellitus (MESH:D003924), vomiting (MESH:D014839), metabolic disorder (MESH:D008659)
- **Chemicals:** cortisol (MESH:D006854), catecholamines (MESH:D002395), free fatty acids (MESH:D005230), blood sugar (MESH:D001786), glucose (MESH:D005947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12913129/full.md

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Source: https://tomesphere.com/paper/PMC12913129