# Mucinous adenocarcinoma with peritoneal carcinomatosis presenting as acute abdomen: a case report

**Authors:** Resul Nusretoğlu, Abdullahi Khalif Ali

PMC · DOI: 10.3389/fonc.2025.1722960 · Frontiers in Oncology · 2026-02-04

## TL;DR

A rare case of ovarian mucinous adenocarcinoma presented as an acute abdomen due to peritoneal spread, successfully treated with surgery and showing good recovery.

## Contribution

This case report highlights the rare presentation of mucinous adenocarcinoma as an acute abdomen and emphasizes the importance of multidisciplinary management.

## Key findings

- A 70-year-old woman with acute abdomen symptoms was diagnosed with mucinous adenocarcinoma and peritoneal carcinomatosis.
- Surgical intervention drained 12 liters of mucinous fluid and confirmed the diagnosis histopathologically.
- The patient showed good recovery at six-month follow-up after multidisciplinary treatment.

## Abstract

Ovarian mucinous cystadenocarcinoma is a rare malignant epithelial tumor, accounting for approximately 10–15% of ovarian carcinomas. It typically presents with nonspecific abdominal symptoms and may reach a large size before detection. Presentation as an acute abdomen is uncommon and usually reflects advanced disease complicated by rupture or extensive peritoneal carcinomatosis.

A 70-year-old postmenopausal woman presented with severe abdominal pain, vomiting, and fever. Laboratory evaluation revealed marked leukocytosis and elevated inflammatory markers. Imaging demonstrated a large multiloculated left adnexal cystic mass measuring 20 × 12 cm, associated with massive ascites and omental thickening. Due to signs of acute abdomen and clinical deterioration, urgent exploratory laparotomy was performed. Intraoperatively, diffuse peritoneal carcinomatosis and a large left ovarian mass were identified, and approximately 12 liters of mucinous fluid were drained. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, infracolic omentectomy, and appendectomy. Histopathological examination confirmed mucinous adenocarcinoma. The postoperative course was uneventful, and the patient demonstrated good recovery at six-month follow-up.

Ovarian mucinous adenocarcinoma may rarely present as an acute abdomen due to extensive peritoneal involvement. Early recognition, thorough exclusion of alternative acute abdominal etiologies, accurate histopathological diagnosis, and multidisciplinary management are essential for optimal outcomes.

## Linked entities

- **Diseases:** ovarian mucinous cystadenocarcinoma (MONDO:0002701), mucinous adenocarcinoma (MONDO:0004957), peritoneal carcinomatosis (MONDO:0700336)

## Full-text entities

- **Genes:** mucin [NCBI Gene 100508689], CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** fever (MESH:D005334), ischemia (MESH:D007511), vomiting (MESH:D014839), hemorrhage (MESH:D006470), intra-abdominal infection (MESH:D059413), malignancy (MESH:D009369), rupture (MESH:D012421), peritoneal carcinomatosis (MESH:D010534), Mucinous tumors (MESH:D018297), epithelial malignancy (MESH:D002277), abdominal pain (MESH:D015746), ruptured ovarian cyst (MESH:D010048), abscess (MESH:D000038), inflammatory (MESH:D007249), mucinous cystadenocarcinoma (MESH:D018282), Ovarian mucinous cystadenocarcinoma (MESH:D010049), purulent (MESH:D003234), infectious (MESH:D003141), Acute abdomen (MESH:D000006), abdominal distension (MESH:D000007), gynecologic disorders (MESH:D005831), drug allergies (MESH:D004342), Ovarian mucinous adenocarcinoma (MESH:D010051), rebound tenderness (MESH:D063806), bowel perforation (MESH:D057112), intestinal obstruction (MESH:D007415), bacterial peritonitis (MESH:D010538), infertility (MESH:D007246), gastrointestinal perforation (MESH:D005767), infection (MESH:D007239), Mucinous adenocarcinoma (MESH:D002288), leukocytosis (MESH:D007964), Adnexal torsion (MESH:D000082843), gastrointestinal primary tumor (MESH:D046152), appendicitis (MESH:D001064), ascites (MESH:D001201), pelvic pain (MESH:D017699), Pseudomyxoma peritonei (MESH:D011553)
- **Chemicals:** platinum (MESH:D010984), oxygen (MESH:D010100), alcohol (MESH:D000438), H&amp;E (MESH:D006371)
- **Species:** Rahnella sp. N (species) [taxon 291580], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12913126/full.md

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Source: https://tomesphere.com/paper/PMC12913126