# Post-intervention sustainability of time-restricted eating versus caloric restriction: a secondary analysis

**Authors:** De-An Chen, Raul Herrera Pena, Niki Oldenburg, Qi Wang, Erika Helgeson, Brad Yentzer, Abdisa Taddese, Nicole LaPage, Emily N. C. Manoogian, Satchinananda Panda, Lisa S. Chow

PMC · DOI: 10.1038/s41366-025-01968-2 · International Journal of Obesity (2005) · 2025-11-28

## TL;DR

This study compared the long-term sustainability of time-restricted eating and calorie restriction for weight management, finding both methods similarly effective but with different challenges.

## Contribution

The study provides new insights into the post-intervention sustainability of TRE versus CR for weight management.

## Key findings

- TRE participants maintained weight post-intervention, while CR participants regained weight by 3 months.
- Both TRE and CR had similar continuation and recommendation rates at 3–6 months.
- TRE improved sleep and digestion, while CR increased food mindfulness but caused anxiety and cravings.

## Abstract

Rising obesity rates necessitate sustainable weight management strategies. Current lifestyle guidelines focus on reducing caloric intake through personalized interventions to promote compliance. This secondary analysis evaluated post-intervention sustainability of time-restricted eating (TRE) versus caloric restriction (CR), hypothesizing that TRE’s “watching the clock” approach may be more sustainable than CR’s “watching calories.” Following a 12-week supervised intervention (TRE: 8-h eating window, n = 29; CR: 15% caloric reduction, n = 26), 41 participants (75%; 24 F/17 M; 23 TRE/18 CR; age 43.1 ± 11.6 years; BMI 34.7 ± 5.4 kg/m²) completed follow-up surveys at 1, 3, and 6 months. TRE participants maintained weight across all follow-ups compared to final intervention weight. CR participants showed significant loss at 1 month (−1.6 ± 2.5 kg, p = 0.02), returning to baseline by 3 months. Both interventions had similar continuation rates (1,3,6 months: TRE: 52%, 36%, 47%; CR: 63%, 57%, 50%; p = 0.60) and recommendation rates (TRE: 81%, 85%, 86%; CR: 88%, 86%, 80%; p = 0.72). TRE participants reported improved sleep, energy, and digestion but experienced morning hunger and scheduling challenges. CR participants noted increased food mindfulness but reported tracking anxiety, cravings, and potential binge eating. Despite limitations including small sample size and self-reported weight, both self-sustained TRE and CR showed similar acceptability and weight maintenance at 3–6 months post-intervention. Clinical Trial Registration: Clinicaltrials.gov NCT04259632.

## Linked entities

- **Diseases:** obesity (MONDO:0011122)

## Full-text entities

- **Diseases:** anxiety (MESH:D001007), binge eating (MESH:D002032), obesity (MESH:D009765)

## Full text

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## Figures

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12913024/full.md

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Source: https://tomesphere.com/paper/PMC12913024