This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
RETRACTION: Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T3‐L1 Cells by Regulating MMP‐2 and MMP‐9
Evidence-Based Complementary and Alternative Medicine

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsGinseng Biological Effects and Applications · Ziziphus Jujuba Studies and Applications · Biochemical Analysis and Sensing Techniques
RETRACTION: J. Oh, H. Lee, D. Park, J. Ahn, S. S. Shin, and M. Yoon, “ Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T3‐L1 Cells by Regulating MMP‐2 and MMP‐9,” Evidence-Based Complementary and Alternative Medicine, 2012 (2012) https://doi.org/10.1155/2012/265023.
The above article, published online on 14 November 2012 in Wiley Online Library (https://www.wileyonlinelibrary.com), has been retracted following by John Wiley & Sons Ltd.
The retraction has been agreed following an investigation of the concerns raised by Penicillium citreoviride and Actinopolyspora biskrensis on PubPeer [1], which identified unexpected similarities between multiple panels of Figure 1. The overlapping features include the following:
- -The image of 3T3‐L1 cells treated with 1 µM Rb2 appears similar to the adipocytes treated with 1 µM of Rg1.
- -The cells treated with 10 µM of Rf have similar features to the adipocytes cultured with 1 µg/mL of GE.
- -The image of cells treated with 10 µM of Rc appears identical to the cells treated with 10 µM of Rg3.
The authors have been contacted to comment on the abovementioned concerns and provide raw data for the images presented in the paper; however, no response was received.
Therefore, the results and integrity of this article can no longer be considered reliable.
The authors were informed of this retraction but did not provide a response.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Penicillium citreoviride and Actinopolyspora biskrensis, “Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T 3-L 1 Cells by Regulating MMP-2 and MMP-9,” Pub Peer, July 2024, https://pubpeer.com/publications/8CE 2FB 37349 C 8FD 7093024 FE 70F 4D 8.10.1155/2012/265023 PMC 351892323258984 · doi ↗ · pubmed ↗
