# The Role of Health Networks in Disseminating Knowledge about Infant HIV Testing in Rural Uganda: Population-Based Sociocentric Network Study

**Authors:** Alison B. Comfort, James Moody, Julian Adong, Carol S. Camlin, Theodore D. Ruel, Scholastic Ashaba, Jessica M. Perkins, Charles Baguma, Emily N. Satinsky, Justus Kananura, E. Betty Namara, Mercy Juliet, Bernard Kakuhikire, Cynthia C. Harper, Alexander C. Tsai

PMC · DOI: 10.1007/s10461-025-04873-x · AIDS and behavior · 2026-02-18

## TL;DR

This study shows that social networks in rural Uganda help spread knowledge about early infant HIV testing, and peer interactions can improve awareness.

## Contribution

The study introduces a sociocentric network approach to understand how knowledge about infant HIV testing spreads in rural communities.

## Key findings

- Having a social tie with correct knowledge increases one's own knowledge about early infant testing.
- Daily contact with social ties is linked to better knowledge about infant HIV testing.
- Network authorities can play a key role in disseminating health information.

## Abstract

Early testing of infants exposed to HIV can significantly decrease mortality for those linked to HIV treatment. Infants exposed to HIV should first be tested at 6 weeks of age, but only 60% are tested as recommended. Little research has focused on the role of social networks in disseminating information about infant HIV testing. We conducted a cross-sectional, sociocentric network study of all adults living in a rural parish in Uganda (N=1,383) and gathered data on socio-demographic characteristics, self-reported HIV status, and knowledge about infant testing recommendations. We administered a culturally-adapted name generator to measure the parish health network. We fitted a multivariable generalized linear regression model with a logit distribution to estimate the association between having at least one social tie with correct knowledge about early infant testing and individual knowledge about infant testing. Having at least one social tie who knew about infant HIV testing at 6 weeks was positively associated with correct knowledge about early infant testing (adjusted odds ratio [aOR] 1.42, 95% confidence interval [CI] 1.07- 1.88, p-value=0.02). Correct knowledge about early infant testing was also associated with having daily contact with social ties (aOR 1.31, 95% CI 1.00-1.71, p-value=0.05) and being considered an authority for health advice within the network (aOR 1.81, 95% CI 1.18-2.77, p-value=0.01). These findings suggest that interventions to enhance peer-to-peer information exchange could increase knowledge about early infant testing, since individuals rely on close, frequently contacted social ties. Network-central individuals can also be engaged to disseminate information about early infant testing

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## Figures

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## References

63 references — full list in the complete paper: https://tomesphere.com/paper/PMC12912738/full.md

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Source: https://tomesphere.com/paper/PMC12912738