# Giant lipoma with an unusual anatomical location successfully managed in a resource-limited setting: a case report

**Authors:** Wondwosen Mengist Dereje, Desalegn Kefale Aegash, Alem Demissie Bogale, Mengist Asmamaw Tegegne

PMC · DOI: 10.1093/jscr/rjag074 · Journal of Surgical Case Reports · 2026-02-17

## TL;DR

A rare case of a giant lipoma in a young man's neck was successfully managed in a resource-limited setting.

## Contribution

This case highlights the unusual presentation and successful management of a giant lipoma in a young male in a resource-limited setting.

## Key findings

- The patient had a 20 × 25 cm lipoma in the posterior neck that developed over three years.
- Delayed presentation is common in resource-limited settings, but accurate diagnosis and management are still possible.
- Giant lipomas can mimic malignancies, emphasizing the importance of proper differentiation for treatment.

## Abstract

Lipomas are benign tumors arising from abnormal proliferation of adipocytes, commonly found in fat-rich regions, though rarely in the head and neck. They usually occur between 40 and 50 years of age, with a slight male predominance. This report presents a 29-year-old male with a giant posterior neck lipoma, emphasizing the need to distinguish it from soft tissue malignancy. The swelling began as a small lump and gradually enlarged to 20 × 25 cm over three years. Initially painless, it later caused cosmetic deformity and psychological distress, leading to social withdrawal and poor self-care. Head and neck lipomas represent a small fraction of cases, and those exceeding 10 cm are classified as giant lipomas. Such large lesions may mimic malignancy, delaying diagnosis. Typically, patients present with a progressive, movable, painless swelling, and delayed presentation is common in resource-limited settings, where accurate differentiation remains vital for proper management.

## Linked entities

- **Diseases:** lipoma (MONDO:0005106)

## Full-text entities

- **Genes:** ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}
- **Diseases:** swelling (MESH:D004487), Madelung's disease (MESH:D008069), Head and neck lipomas (MESH:D006258), weight loss (MESH:D015431), angiolipoma (MESH:D018206), benign tumors (MESH:D009369), emaciated (MESH:D004614), myxoid liposarcoma (MESH:D018208), malnutrition (MESH:D044342), Liposarcomas (MESH:D008080), posterior (MESH:D001041), lipomatosis (MESH:D008068), trauma (MESH:D014947), Giant lipoma (MESH:D008067), dermatophytosis (MESH:D014005), lipoblastoma (MESH:D062689), fever (MESH:D005334), intramuscular angioma (MESH:D006391), necrosis (MESH:D009336), HIV-related lipodystrophy (MESH:D039682), Cushing's disease (MESH:D047748), paresthesia (MESH:D010292), depressed (MESH:D003866), myxoma (MESH:D009232), cosmetic deformity (MESH:D009140)
- **Chemicals:** ciprofloxacin (MESH:D002939), fat (MESH:D005223)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12911508/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12911508/full.md

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Source: https://tomesphere.com/paper/PMC12911508