# Iatrogenic Nerve Injuries in Head and Neck Surgeries: A Systematic Review of Mechanisms, Outcomes, and Prevention Strategies

**Authors:** Aymen J Mohamed, Ruba Mohamedahmed, Mariem Aboussaid, Rayan Adam Mahdi Edrees, M-Malek A Alghawee, Asim Ahmed

PMC · DOI: 10.7759/cureus.101768 · Cureus · 2026-01-18

## TL;DR

This review explores how nerve injuries during head and neck surgeries can be prevented by identifying common injury mechanisms and effective prevention strategies.

## Contribution

The study provides a systematic review of iatrogenic nerve injury mechanisms and prevention strategies in head and neck surgeries.

## Key findings

- Traction on visually intact nerves is the main cause of iatrogenic nerve injury.
- Early microsurgical repair improves recovery outcomes compared to delayed intervention.
- Intraoperative nerve monitoring is most beneficial in complex surgical cases.

## Abstract

Iatrogenic nerve injury in head and neck surgery remains a substantial yet potentially preventable source of morbidity across endocrine, otolaryngologic, and related procedures. This systematic review synthesized evidence to identify the nerves most frequently affected, delineate operative mechanisms of injury, describe the clinical course, and evaluate preventive strategies. Traction on visually intact nerves emerged as the predominant mechanism, with additional contributions from thermal injury, compression, ischemia, and entrapment by suture or clip. The recurrent laryngeal, facial, trigeminal (inferior alveolar and lingual), spinal accessory, and lower cranial nerves were identified as the principal structures at risk, with procedure type influencing the pattern and severity of deficits. Prevention centered on deliberate visual identification, meticulous dissection along natural planes, and risk-stratified use of intraoperative nerve monitoring, which proved most beneficial in complex or reparative fields. While most postoperative deficits resolved over time, a subset persisted, impairing voice, swallowing, facial movement, shoulder function, or orofacial sensation. Early, tension-free microsurgical repair was associated with superior recovery compared to delayed intervention. Despite heterogeneity in definitions, assessment timing, and follow-up, these findings support a practical prevention framework that integrates precise anatomical techniques, gentle handling, structured monitoring in high-risk cases, and timely referral for persistent deficits to minimize avoidable nerve injury and improve long-term outcomes.

## Full-text entities

- **Diseases:** H&amp;N nerve injury (MESH:D000080902), stylomastoid foramen (MESH:C000630779), PICOS (MESH:D011248), maxillofacial trauma (MESH:D008446), Iatrogenic nerve injury (MESH:D007049), SAN (MESH:D061227), neuropathic pain (MESH:D009437), aspiration (MESH:D011015), osteomyelitis (MESH:D010019), dysfunction (MESH:D006331), dysesthesia (MESH:D010292), H&amp;N (MESH:D000848), neuromuscular blockade (MESH:D020879), facial palsy (MESH:D005158), Injury (MESH:D014947), dysphonia (MESH:D055154), Facial nerve injuries (MESH:D020220), voice disorders (MESH:D014832), RLN (MESH:D061226), pain (MESH:D010146), cranial and peripheral nerve injuries (MESH:D059348), sensory dysfunction (MESH:D012678), Shoulder pain and dysfunction (MESH:D020069), weakness (MESH:D018908), cancer (MESH:D009369), somatosensory disturbance (MESH:D020886), neurotoxicity (MESH:D020258), Trigeminal nerve injuries (MESH:D061221), Head and Neck Surgeries (MESH:D006258), osteoradionecrosis (MESH:D010025), palsies (MESH:D010243), vestibular schwannoma (MESH:D009464), CNI (MESH:D020209), IONM (MESH:C537568), ischemia (MESH:D007511), LN injuries (MESH:D061222), recurrent laryngeal nerve palsy (MESH:D014826), neurosensory disturbance (MESH:D006319)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12910528/full.md

## References

52 references — full list in the complete paper: https://tomesphere.com/paper/PMC12910528/full.md

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Source: https://tomesphere.com/paper/PMC12910528