# Delayed Splenic Rupture 48 Hours After a Colonoscopy: A Case Report

**Authors:** Parthena Samara, Sergios Konstantinidis, Anastasios Katsourakis, Michael N Chrysikos, Konstantinos Peidis, Iosif Hadjis

PMC · DOI: 10.7759/cureus.101763 · Cureus · 2026-01-18

## TL;DR

A 59-year-old woman experienced a rare case of splenic rupture 48 hours after a colonoscopy, highlighting the importance of considering this complication in post-procedure patients.

## Contribution

This case report adds to the understanding of delayed splenic rupture as a rare but serious complication of colonoscopy.

## Key findings

- A 59-year-old woman presented with splenic rupture 48 hours after colonoscopy.
- Computed tomography confirmed hemoperitoneum due to splenic injury.
- The patient recovered after undergoing splenectomy.

## Abstract

Splenic rupture following colonoscopy, although uncommon, is a potentially life-threatening complication that all medical doctors should consider in their differential diagnosis. Several risk factors contribute to this condition, including exogenous elements such as the endoscopist's experience, patient positioning, medications, mechanical force during endoscope advancement, and technique at the splenic flexure, as well as endogenous factors like patient anatomy, perisplenic adhesions, inflammatory or infectious diseases, hematological disorders, malignancy, and interventions such as biopsy or polypectomy. We report a case of a 59-year-old woman who presented to the emergency department 48 hours after a colonoscopy with left upper quadrant abdominal pain, weakness, and pallor. Laboratory tests showed anemia. She had ongoing pain and hemodynamic instability, and a computed tomography revealed hemoperitoneum caused by splenic rupture. The patient underwent splenectomy and subsequently recovered without complications. Although colonoscopy remains the gold standard for diagnosing and managing colorectal diseases with a low incidence of serious adverse events, physicians should maintain a high index of suspicion for splenic injury in patients presenting with anemia and recent large bowel endoscopy.

## Linked entities

- **Diseases:** anemia (MONDO:0002280), malignancy (MONDO:0004992)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** anemia (MESH:D000740), adhesions (MESH:D000267), drop in blood pressure (MESH:D006973), hematological diseases (MESH:D006402), colorectal diseases (MESH:D015179), peritoneal (MESH:D010538), splenic laceration (MESH:D022125), dizziness (MESH:D004244), hypovolemia (MESH:D020896), embolization (MESH:D004617), abdominal tenderness (MESH:D000007), inflammatory bowel disease (MESH:D015212), polyp (MESH:D011127), bowel perforation (MESH:D057112), Splenic injuries (MESH:D013158), allergy (MESH:D004342), tenderness (MESH:D063806), infectious diseases (MESH:D003141), complication (MESH:D008107), inflammatory (MESH:D007249), injuries (MESH:D014947), hematoma (MESH:D006406), syncope (MESH:D013575), hemoperitoneum (MESH:D006465), pain (MESH:D010146), loss of consciousness (MESH:D014474), malignancy (MESH:D009369), pseudoaneurysm (MESH:D017541), weakness (MESH:D018908), pneumoperitoneum (MESH:D011027), Splenic Rupture (MESH:D013161), abdominal pain (MESH:D015746), ureteric stones (MESH:D014515), pancreatitis (MESH:D010195), contrast media (MESH:D005119), bleeding (MESH:D006470), splenomegaly (MESH:D013163), fatigue (MESH:D005221), hemorrhoids (MESH:D006484)
- **Chemicals:** cefoxitin (MESH:D002440)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12910406/full.md

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Source: https://tomesphere.com/paper/PMC12910406