# CDS-PD: a novel clinical decision support platform for Parkinson’s disease

## TL;DR

A new digital tool called CDS-PD helps doctors and researchers apply Parkinson’s disease diagnostic criteria more consistently and accurately.

## Contribution

A validated clinical decision support platform for Parkinson’s disease based on MDS-PD criteria is developed and tested.

## Key findings

- CDS-PD shows high agreement with expert neurologists in diagnosing Parkinson’s disease.
- The platform is modular, extensible, and suitable for real-time application of diagnostic algorithms.
- CDS-PD supports standardized electronic implementation of MDS-PD criteria for clinical use.

## Abstract

The Movement Disorders Society clinical diagnostic criteria for Parkinson’s disease (MDS-PD) allow highly sensitive and specific diagnosis of Parkinson’s disease. However, their adoption has been limited due to lack of a clinical decision support (CDS) tool to support clinicians and researchers in systematically and accurately applying the MDS-PD criteria. We have developed and performed preliminary validation of a CDS platform for PD (CDS-PD) as a modular and extensible informatics platform with comprehensive functionalities for recording relevant patient information. We have performed real-time application of diagnostic algorithm of the MDS-PD criteria. The CDS-PD platform shows high concordance with application of the MDS-PD criteria by experienced movement disorders neurologists for established PD (disease duration ≥ 5 years). The CDS-PD platform is a step towards realizing the standardized electronic implementation of the MDS-PD criteria for PD patient care and clinical trials at point-of-care. The CDS-PD platform can be accessed after registration at weblink https://www.cdspd.org.

The online version contains supplementary material available at 10.1038/s41598-026-37316-1.