# Multiple Health Outcomes of Daytime Napping: A Comprehensive Umbrella Review

**Authors:** Pengqiang Du, Jiqian Li, Zixin Hua, Yiqi Sun, Siyang Song, Yin Liao, Sheng Cheng, Xingang Li

PMC · DOI: 10.3389/phrs.2026.1609013 · 2026-02-03

## TL;DR

This study reviews how daytime napping affects health, finding that short naps improve cognition and reduce fatigue, while long naps increase risks of heart disease and diabetes.

## Contribution

The study provides a comprehensive umbrella review of napping's health effects, identifying optimal nap durations for cognitive and physical benefits.

## Key findings

- Napping <60 minutes improves cognition and reduces fatigue without increasing chronic disease risks.
- Napping >60 minutes increases risks of coronary heart disease, diabetes, and obesity by 20-30%.
- Short naps (20-30 minutes) enhance athletic performance and recovery, especially in sleep-deprived individuals.

## Abstract

This umbrella review aimed to clarify the dose-response relationship between napping duration and multiple health outcomes.

Following JBI guidelines, the review included studies from PubMed, Web of Science, the Cochrane Library, and EMBASE. Data on health outcomes, effect sizes, and study characteristics were extracted, and the quality of the studies was assessed using AMSTAR-2 and GRADE. A random effects model and a sensitivity analysis were used to evaluate the associations.

This umbrella review identified 16 meta-analyses encompassing 244 health-related outcomes. Napping for <60 min maximizes cognitive enhancement (SMD = 0.69, 95% CI: 0.37–1.00) and reduces fatigue, while minimizing the risk of all-cause mortality and chronic diseases. Napping for >60 min correlates with a 30% higher risk of coronary heart disease and a 20% increased risk of diabetes and obesity; short naps (20–30 min) improve athletic performance (SMD = 0.99, 95% CI: 0.67–1.31) and recovery, particularly in sleep-deprived individuals.

Limiting nap duration to ≤60 min may optimize cognitive and physical benefits while reducing chronic disease risks. For individuals with chronic conditions, it is prudent to avoid prolonged naps (>60 min) and prioritize nighttime sleep quality.

## Linked entities

- **Diseases:** coronary heart disease (MONDO:0005010), diabetes (MONDO:0005015), obesity (MONDO:0011122)

## Full-text entities

- **Genes:** IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}, CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, SOD1 (superoxide dismutase 1) [NCBI Gene 6647] {aka ALS, ALS1, HEL-S-44, IPOA, SOD, STAHP}, IER3 (immediate early response 3) [NCBI Gene 8870] {aka DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1}
- **Diseases:** hypertension (MESH:D006973), colorectal cancer (MESH:D015179), excessive sleepiness (MESH:D006970), XL (MESH:D000080345), CVD (MESH:D002318), dementia (MESH:D003704), muscle soreness (MESH:D063806), cardiac diseases (MESH:D006331), type 2 diabetes (MESH:D003924), sleep deprivation (MESH:D012892), depression (MESH:D003866), cognitive dysfunction (MESH:D003072), chronic (MESH:D002908), sleep disorders (MESH:D012893), impairments in alertness (MESH:D000071064), PD (MESH:D010300), coronary heart (MESH:D003327), Sleep inertia (MESH:D014593), chronic inflammation (MESH:D007249), hyperlipidemia (MESH:D006949), metabolic syndrome (MESH:D024821), MCI (MESH:D060825), diabetes (MESH:D003920), endothelial dysfunction (MESH:D014652), Cancer (MESH:D009369), fatigue (MESH:D005221), stroke (MESH:D020521), reduced language fluency (MESH:D007806), Obesity (MESH:D009765), NRSIs (MESH:C580335), hypoxia (MESH:D000860), metabolic diseases (MESH:D008659), sympathetic hyperactivity (MESH:D006948)
- **Chemicals:** melatonin (MESH:D008550), Nap (MESH:C043186), cortisol (MESH:D006854)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12909254/full.md

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Source: https://tomesphere.com/paper/PMC12909254