# Ultra-hypofractionation for node-positive prostate cancer: pushing boundaries and redefining standards

**Authors:** Jennifer Le Guévelou, Mathilde Jeandin, Antonio Angrisani, Davide Giovanni Bosetti, Mohamed Shelan, Thomas Zilli

PMC · DOI: 10.1038/s41391-025-00976-7 · 2025-05-08

## TL;DR

This paper reviews recent advances in radiotherapy for prostate cancer that has spread to nearby lymph nodes, focusing on ultra-hypofractionated treatment.

## Contribution

The paper highlights the role of ultra-hypofractionated radiotherapy as a novel approach in treating node-positive prostate cancer.

## Key findings

- Advances in imaging and radiation therapy have improved treatment standards for node-positive prostate cancer.
- Ultra-hypofractionated radiotherapy is emerging as a promising therapeutic option in this context.

## Abstract

Radiotherapy is a cornerstone in the management of node-positive prostate cancer. Advances in imaging modalities and radiation therapy techniques have led to the evolution of treatment standards for this patient population. This review aims to explore the therapeutic advancements of the past decade, with a focus on the role of ultra-hypofractionated radiotherapy in node-positive prostate cancer.

## Linked entities

- **Diseases:** prostate cancer (MONDO:0005159)

## Full-text entities

- **Diseases:** node-positive prostate cancer (MESH:D011471)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12909117/full.md

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Source: https://tomesphere.com/paper/PMC12909117