# (Remembering) Vector Coding of Boundaries and Objects in the Subiculum

**Authors:** Colin Lever

PMC · DOI: 10.1002/hipo.70074 · 2026-02-16

## TL;DR

This paper reviews how neurons in the hippocampus and subiculum represent spatial information, focusing on boundary and object coding in rodents.

## Contribution

The paper introduces vector trace cells, a new type of boundary vector cell with memory capabilities.

## Key findings

- CA1 place cells show geometric responses and discrimination learning.
- Subiculum contains boundary vector cells, boundary-off cells, and vector trace cells.
- Vector trace cells combine boundary coding with memory.

## Abstract

This review offers a personal and historical perspective on spatial representations of the local environment in hippocampal regions CA1 and subiculum, as derived from extracellular electrophysiological recording of neurons in these regions in freely behaving rodents. I focus upon geometric responses and discrimination learning in CA1 place cells, and upon boundary vector cells, boundary‐off cells, and vector trace cells in the subiculum. Vector trace cells are a type of boundary vector cell with an additional memory capability.

## Full-text entities

- **Genes:** Ca3 (carbonic anhydrase 3) [NCBI Gene 54232] {aka Car3}, Ca1 (carbonic anhydrase 1) [NCBI Gene 310218] {aka CA-I, Car1}
- **Diseases:** Anxiety (MESH:D001007), HD (MESH:D006816), IVF (MESH:C537182), BVCs (MESH:D000079426)
- **Chemicals:** BVC (-), scopolamine (MESH:D012601)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Felis catus (cat, species) [taxon 9685], Rattus norvegicus (brown rat, species) [taxon 10116]
- **Mutations:** G01342X

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12908435/full.md

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Source: https://tomesphere.com/paper/PMC12908435