Giant pedunculated cellular angiofibroma of the labia majora: a case report

TL;DR

A rare benign tumor called cellular angiofibroma was diagnosed and surgically removed from a 65-year-old woman's labia majora after growing for 5 years.

Contribution

This paper presents a rare case of giant pedunculated cellular angiofibroma with a long growth duration and successful surgical management.

Findings

The tumor was confirmed as a benign myxoid spindle cell neoplasm through histopathological examination.

Surgical excision and reconstruction led to an uneventful recovery despite the tumor's large size.

The case underscores the diagnostic challenges and treatment approach for cellular angiofibroma.

Abstract

Cellular angiofibroma is a rare, benign mesenchymal tumor most commonly arising in the vulvovaginal region in middle-aged to elderly women. Despite its indolent nature, it is frequently misdiagnosed due to a nonspecific clinical presentation and its resemblance to other vulvar masses.

We present a case of a 65-year-old postmenopausal woman with a neglected, slowly growing giant pedunculated mass on her left labia majora that developed over 5 years. The patient underwent surgical excision and cosmetic reconstruction, with an uneventful postoperative recovery. Histopathological examination confirmed a benign myxoid spindle cell neoplasm consistent with cellular angiofibroma.

This case highlights the challenges in the diagnosis of cellular angiofibroma owing to the tumor’s often nonspecific presentation and emphasizes the importance of surgical excision as the standard treatment, despite a low reported risk of recurrence even with positive surgical margins.

Figures