# Effectiveness of remote monitoring for patients with a high risk of cardiovascular disease: a 12-month matched cohort study in primary care

**Authors:** Nicoline E van Hattem, Margot M Rakers, Eric G Hiddink, Saskia le Cessie, Just A H Eekhof, Frank den Heijer, Niels H Chavannes, Hendrikus J A van Os, Douwe E Atsma, Tobias N Bonten

PMC · DOI: 10.1093/ehjdh/ztag014 · 2026-01-22

## TL;DR

A study found that remote monitoring helped manage blood pressure and weight in high-risk cardiovascular patients over 12 months.

## Contribution

The study introduces a remote monitoring system (CVRM-Box) and evaluates its impact on cardiovascular risk management in primary care.

## Key findings

- Remote monitoring led to significant reductions in blood pressure and weight in home measurements.
- The intervention increased antihypertensive medication use and decreased consultation frequency.
- Office-measured blood pressure showed no significant change despite home monitoring improvements.

## Abstract

This study aimed to evaluate the effect of remote monitoring using the Cardiovascular Risk Management (CVRM)-Box on blood pressure control, weight management, medication prescriptions, and consultation frequency in primary care patients at high risk of cardiovascular disease (CVD).

In this matched cohort study, patients with a > 5% 10-year CVD mortality risk in primary care (2020–2024) were compared to propensity score-matched controls over 12 months. The CVRM-Box included smartphone-connected devices (blood pressure monitor, weighing scale, activity tracker) linked to general practitioner electronic health records.

Compared to controls, the intervention group showed modest reductions in office-measured systolic {−1.1 mmHg [95% confidence interval (CI), −3.7 to −1.5]; P = 0.39} and diastolic blood pressure [−0.04 mmHg (95% CI, −1.6 to 1.5); P = 0.96]. Sensitivity analyses yielded similar results. However, CVRM-Box assessments showed reductions in systolic [−5.5 mmHg (95% CI, −7.6 to −3.3); P < 0.001] and diastolic blood pressure [−3.8 mmHg (95% CI, −5.1 to −2.4); P < 0.001]. The intervention group also experienced greater reductions in weight [−0.9 kg (95% CI, −1.6 to −0.2); P = 0.01] and body mass index [−0.3 kg/m² (95% CI, −0.5 to −0.01); P = 0.007]. Additionally, antihypertensive medication use increased [0.12 (95% CI, 0.06 to 0.23); P = 0.04], while consultation frequency decreased (rate ratio 0.82; P = 0.002).

While office measurements showed no additional blood pressure reduction, CVRM-Box measurements demonstrated significant decreases. The intervention also improved target blood pressure achievement, promoted weight reduction, increased antihypertensive use, and reduced consultation frequency.

Graphical Abstract

## Linked entities

- **Diseases:** cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** CVD (MESH:D002318), weight (MESH:D015431), blood pressure (MESH:D006973)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12907927/full.md

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Source: https://tomesphere.com/paper/PMC12907927