# Additional Cover

## TL;DR

The paper explores how aging is linked to atavistic genetic expression patterns using phylogenetic evidence.

## Contribution

It introduces a novel meta-phylostratigraphic approach to study genetic dissociation during aging.

## Key findings

- Aged tissues show increased expression of ancient genes typically seen in early developmental stages.
- This genetic dissociation correlates with cellular and tissue-level aging processes.
- The findings suggest a reactivation of ancestral genetic programs during aging.

## Abstract

The cover image is based on the article Atavistic Genetic Expression Dissociation (AGED) During Aging: Meta‐Phylostratigraphic Evidence of Cellular and Tissue‐Level Phylogenetic Dissociation by Léo Pio‐Lopez and Michael Levin, https://doi.org/10.1111/acel.70305.