# Featured Cover

**Authors:** Matías Fuentealba, JangKeun Kim, Jeremy Wain Hirschberg, Bader Shirah, Eliah G. Overbey, Christopher Mason, David Furman

PMC · DOI: 10.1111/acel.70415 · 2026-02-15

## TL;DR

This paper explores how space exposure affects human aging by studying epigenetic changes in astronauts.

## Contribution

The study introduces astronauts as a novel model for understanding human aging through epigenetic age analysis.

## Key findings

- Epigenetic age changes were observed in astronauts after space missions.
- Space exposure may accelerate or alter biological aging processes.

## Abstract

Cover legend: The cover image is based on the article Astronauts as a Human Aging Model: Epigenetic Age Responses to Space Exposure by Matías Fuentealba et al., https://doi.org/10.1111/acel.70360.

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12906796/full.md

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Source: https://tomesphere.com/paper/PMC12906796