# Fascicular Ventricular Tachycardia: An Electrophysiological Paradox

**Authors:** Neeraj Joshi, Tom Harris, Harriet Guthrie, Gaurav Joshi, James Rosengarten

PMC · DOI: 10.7759/cureus.101647 · 2026-01-15

## TL;DR

A 27-year-old man with fascicular ventricular tachycardia showed unique ECG patterns and treatment responses, highlighting the need for further research on obesity's impact on ablation outcomes.

## Contribution

The paper presents a novel case of fascicular VT with unique electrophysiological characteristics and treatment challenges.

## Key findings

- The patient exhibited fascicular VT with right bundle branch block and axis deviation on ECG.
- The patient responded to verapamil but not adenosine, consistent with macroscopic reentry circuit origin.
- Obesity was considered a potential factor affecting ablation efficacy, prompting delayed intervention.

## Abstract

We present a case of fascicular ventricular tachycardia (VT) in a 27-year-old man. Fascicular VT arises within the fascicles of the left bundle of His and is associated with right bundle branch block and axis deviation on ECG. Fascicular VT can often be mislabelled as a narrow-complex tachycardia due to the proximity of the arrhythmic origin to the normal conduction system, creating a widened, but not classically “broad,” QRS complex, as occurred in our case. Our patient was resistant to adenosine but sensitive to verapamil, as is characteristic of fascicular VT owing to its origin in a macroscopic reentry circuit within the left bundle of His. Indeed, the patient developed recurrences of fascicular VT whenever verapamil doses were missed. Due to the potential for future hemodynamic instability and myocardial ischemia associated with VT, ablation was considered as a long-term management option for this patient. However, because of his high BMI and the associated theoretical reduction in efficacy, ablation was delayed until the patient achieved weight loss. Further research is needed to determine whether obesity affects ablation outcomes in fascicular VT.

## Linked entities

- **Chemicals:** adenosine (PubChem CID 60961), verapamil (PubChem CID 2520)
- **Diseases:** ventricular tachycardia (MONDO:0005477), myocardial ischemia (MONDO:0024644)

## Full-text entities

- **Diseases:** Fascicular VT (MESH:D017180), arrhythmic (OMIM:212500), obesity (MESH:D009765), tachycardia (MESH:D013610), right bundle branch block (MESH:D002037), myocardial ischemia (MESH:D017202), weight loss (MESH:D015431)
- **Chemicals:** verapamil (MESH:D014700), adenosine (MESH:D000241)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12906639/full.md

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Source: https://tomesphere.com/paper/PMC12906639