# Frontiers and literature review on non-aspiration stroke-associated infections

## TL;DR

This paper reviews non-aspiration infections in stroke patients, focusing on risk factors, causes, and treatments to improve clinical understanding and outcomes.

## Contribution

The paper provides a comprehensive review of non-aspiration stroke-associated infections, highlighting their prevalence and management despite the absence of typical risk factors.

## Key findings

- Approximately 30% of stroke patients develop infections, mainly respiratory and urinary tract infections.
- Non-aspiration stroke-associated infections occur even in patients without aspiration or related risk factors.
- The paper identifies risk factors, pathophysiology, and treatment strategies for non-aspiration stroke-associated infections.

## Abstract

Stroke-associated infection (SAI) is a significant complication of stroke, with approximately 30% of stroke patients developing infections, primarily respiratory and urinary tract infections. These infections can severely impact prognosis and increase the economic burden. While dysphagia is a known independent risk factor for stroke-associated pneumonia, research shows that stroke patients without aspiration or related risk factors, such as dysphagia and impaired consciousness, also exhibit a high incidence of non-aspiration stroke-associated infections (NA-SAI). This comprehensive article meticulously examines and reviews the risk factors, pathophysiological underpinnings, and therapeutic strategies for NA-SAI, with the aim of enhancing clinicians' comprehension and management of this condition.