# Magnesium Toxicity in an Obstetric Patient Due to Preeclampsia-Related Renal Dysfunction Despite Administration of a Standard Pritchard Regimen: A Case Report

## TL;DR

A pregnant woman with eclampsia and kidney issues developed magnesium toxicity after standard treatment, requiring cesarean section, ventilation, and dialysis.

## Contribution

Highlights magnesium toxicity risk in preeclampsia patients with renal dysfunction despite standard treatment protocols.

## Key findings

- Magnesium toxicity occurred in a preeclampsia patient with renal dysfunction despite standard magnesium sulfate treatment.
- Emergency cesarean section, mechanical ventilation, and hemodialysis were required for successful management.
- Undetected hypermagnesemia can lead to severe maternal and fetal complications.

## Abstract

Magnesium toxicity could occur in the treatment of preeclampsia/eclampsia, especially when the patient has coexisting renal impairment. If undetected and promptly treated, hypermagnesemia can cause severe fetomaternal complications and death.

We present the case of a 22-year-old pregnant woman at 32 weeks of gestation, who was referred to our hospital with eclampsia, treated with intramuscular magnesium sulfate following a standard Pritchard regimen. An emergency cesarean section was carried out under general anesthesia due to multiorgan dysfunction. Following the cesarean delivery, she was successfully managed with mechanical ventilation and hemodialysis.