# Acute Acalculous Cholecystitis as the First Manifestation of Systemic Lupus Erythematosus in a Young Man: A Case Report and Review of Literature

## TL;DR

A young man's first sign of lupus was a rare type of gallbladder inflammation, highlighting the need for careful diagnosis to avoid unnecessary surgery.

## Contribution

This case report highlights acute acalculous cholecystitis as a rare initial sign of systemic lupus erythematosus.

## Key findings

- Acute acalculous cholecystitis can be the first manifestation of systemic lupus erythematosus.
- Prompt immunosuppressive therapy resolved symptoms and led to the correct diagnosis.

## Abstract

Acute acalculous cholecystitis can rarely be the initial manifestation of systemic lupus erythematosus. Awareness of this atypical presentation is essential to avoid unnecessary surgical intervention. Prompt recognition and initiation of immunosuppressive therapy may resolve symptoms and help establish the correct underlying diagnosis.