# LAV-BPIFB4 reverses progeria-associated cardiac aging by restoring diastolic function and reducing senescence

**Authors:** Unbin Chae, Young-Ho Park, Taeho Kwon, Kyung-Sook Chung, Sun-Uk Kim

PMC · DOI: 10.7150/ijbs.129092 · International Journal of Biological Sciences · 2026-01-29

## Full-text entities

- **Genes:** BPIFB4 (BPI fold containing family B member 4) [NCBI Gene 149954] {aka C20orf186, LPLUNC4, RY2G5, dJ726C3.5}
- **Diseases:** progeria (MESH:D011371)

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## References

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Source: https://tomesphere.com/paper/PMC12905633