# Complete Resection of a Giant Mediastinal Liposarcoma Extending Into Both Pleural Cavities via Median Sternotomy: A Case Report

**Authors:** Shin‐nosuke Watanabe, Daisuke Kimura, Takahiro Sasaki, Shuta Kimura, Chisaki Ichinohe, Shiori Ono, Hirose Imai, Masahito Minakawa

PMC · DOI: 10.1002/ccr3.72017 · Clinical Case Reports · 2026-02-14

## TL;DR

This case report describes the complete removal of a large mediastinal liposarcoma through a median sternotomy.

## Contribution

The report highlights a successful R0 resection of a giant mediastinal liposarcoma extending into both pleural cavities.

## Key findings

- Complete resection of a giant mediastinal liposarcoma was achieved via median sternotomy.
- Early diagnosis is crucial to avoid extensive and highly morbid surgeries.

## Abstract

Surgical resection is the primary treatment for giant mediastinal liposarcoma. However, aggressive R0 resection involving major nerves can lead to fatal functional loss. Clinicians must balance oncological radicality with functional preservation, as early diagnosis remains the most critical factor for avoiding highly morbid, extensive surgeries.

## Linked entities

- **Diseases:** mediastinal liposarcoma (MONDO:0003601)

## Full-text entities

- **Diseases:** Mediastinal Liposarcoma (MESH:D008480)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12905538/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12905538/full.md

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Source: https://tomesphere.com/paper/PMC12905538