# From Endometriosis to Encapsulation: A Case Report of Endometriosis Causing Sclerosing Encapsulating Peritonitis

**Authors:** Lexi Frankel, Kristen Stearns, Anna Kuan-Celarier, David Childs, Janelle Moulder

PMC · DOI: 10.1155/crog/5805116 · Case Reports in Obstetrics and Gynecology · 2026-02-13

## TL;DR

This case report describes a rare complication of endometriosis called sclerosing encapsulating peritonitis, which caused severe symptoms and required major surgery.

## Contribution

The paper presents a rare case linking endometriosis to sclerosing encapsulating peritonitis, emphasizing diagnostic challenges and management strategies.

## Key findings

- Endometriosis can lead to sclerosing encapsulating peritonitis, a rare and severe condition.
- The patient required extensive surgical intervention due to recurrent complications.
- Endometriosis-related ascites can mimic malignancy, complicating diagnosis.

## Abstract

Sclerosing encapsulating peritonitis is a rare complication of endometriosis that has sparsely been described in the literature. It involves the development of a thick gray‐white fibrotic membrane, which partially or completely encases the small bowel and can spread intraperitoneally to involve surrounding organs, leading to significant morbidity and mortality. This case describes a 33‐year‐old female with long‐standing, biopsy‐proven stage IV endometriosis who developed recurrent bloody ascites and sclerosing encapsulating peritonitis, leading to multiple hospitalizations for infectious complications and ultimately requiring extensive surgical intervention. This case exemplifies the diagnostic challenge posed by endometriosis‐related ascites, which can mimic malignancy, and highlights the need for awareness of atypical presentations, multidisciplinary management, and individualized surgical decision‐making in advanced disease.

## Linked entities

- **Diseases:** endometriosis (MONDO:0005133), sclerosing encapsulating peritonitis (MONDO:1010131)

## Full-text entities

- **Diseases:** malignancy (MESH:D009369), Endometriosis (MESH:D004715), Peritonitis (MESH:D010538), ascites (MESH:D001201)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12905461/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12905461/full.md

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Source: https://tomesphere.com/paper/PMC12905461