# Problem-, resources- and goals-oriented (PRoGO) approach in psychiatry: illustrated by the case of Ludwig II of Bavaria

**Authors:** Stefan Leucht, John M. Davis, Kerem Böge, Amr ElDeeb, Wolfgang Strube, Hans Förstl

PMC · DOI: 10.1007/s00406-025-02192-9 · European Archives of Psychiatry and Clinical Neuroscience · 2026-01-21

## TL;DR

This paper introduces a new approach to psychiatry that focuses on individual problems, resources, and goals, using the case of Ludwig II of Bavaria to demonstrate its potential.

## Contribution

The PRoGO approach offers a personalized alternative to traditional categorical psychiatric classifications.

## Key findings

- The PRoGO approach allows for a more nuanced characterization of patients.
- It can guide personalized treatment planning by focusing on individual problems and resources.
- The case of Ludwig II illustrates the practical application of this method.

## Abstract

Mental health issues are dimensional in nature, yet both ICD-11 and DSM-5 are categorical classifications, leaving many patients not fitting into them. Using Bavaria’s “fairy-tale” king Ludwig II—whose diagnosis remains debated—as an example, we illustrate how the Problem-, Resources-, and Goal-Oriented (PRoGO) approach can lead to a better characterisation of patients and guide personalized treatment planning.

## Full-text entities

- **Diseases:** impulsivity (MESH:D007174), obsessive-compulsive symptoms (MESH:D009771), depression (MESH:D003866), social anxiety (MESH:D000072861), aggressive outbursts (MESH:D010554), frontotemporal dementia (MESH:D057180), CBT (MESH:D003072), hallucinations (MESH:D006212), frontal lobe dysfunction (MESH:D001927), mental problems (MESH:D008607), death (MESH:D003643), delusions (MESH:D063726), psychosis (MESH:D011618), Mental health (OMIM:603663), social dysfunction (MESH:D000067404), binge-eating (MESH:D002032), dead (MESH:D001926), schizotypal disorder (MESH:D012569), Obesity (MESH:D009765), SL (MESH:C564794), neurodegenerative (MESH:D019636), headaches (MESH:D006261), Ludwig (MESH:D008158), schizophrenia spectrum disorders (MESH:D019967), pain (MESH:D010146), paranoia (MESH:D010259), substance use disorders (MESH:D019966), Psychiatric (MESH:D001523), Insomnia (MESH:D007319), infantile meningitis (MESH:D008580), schizophrenia (MESH:D012559), Anxiety (MESH:D001007), chronic headaches (MESH:D020773)
- **Chemicals:** Alcohol (MESH:D000438), amisulpride (MESH:D000077582), PRoGO (-), Metformin (MESH:D008687), chloral-hydrate (MESH:D002697), opiates (MESH:D053610)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

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Source: https://tomesphere.com/paper/PMC12904916