# Discovery Beyond the “Undiscovered Country”: Re-Exploring the Right Ventricle Through Metabolomics and Cardiac Magnetic Resonance

**Authors:** Yue-Hin Loke

PMC · DOI: 10.1016/j.jacasi.2025.12.002 · JACC Asia · 2025-08-29

## Full-text entities

- **Genes:** MTOR (mechanistic target of rapamycin kinase) [NCBI Gene 2475] {aka FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS}
- **Diseases:** atrial septal defects (MESH:D006344), overload (MESH:D019190), myocardial fibrosis (MESH:D005355), congenital and pulmonary vascular disease (MESH:D014652), rTOF (MESH:D013771), pulmonary regurgitation (MESH:D011665), RV (MESH:C535682), abnormalities (MESH:D000014), PAH (MESH:D000081029), cardiovascular disease (MESH:D002318), insulin resistance (MESH:D007333), congenital heart disease (MESH:D006330), tricuspid insufficiency (MESH:D014262), heart failure (MESH:D006333), cardiac dysfunction (MESH:D006331), impaired exercise tolerance (MESH:D018149)
- **Chemicals:** oxygen (MESH:D010100), choline (MESH:D002794), carbon (MESH:D002244), BCAA (MESH:D000597), nitric oxide (MESH:D009569), S-adenosylhomocysteine (MESH:D012435), alpha-ketoacid (-), superoxide (MESH:D013481), acyl-carnitines (MESH:C116917), arginine (MESH:D001120), lipid (MESH:D008055), dimethylglycine (MESH:C025138), glucose (MESH:D005947), reactive oxygen species (MESH:D017382)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12904814/full.md

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Source: https://tomesphere.com/paper/PMC12904814