# ANEURYSMAL BONE CYST: A CASE SERIES OF AN AGGRESSIVE BENIGN TUMOR

**Authors:** Caio Falk Giannotti, Nathalia Sundin Palmeira de Oliveira, Jairo Greco Garcia, Marcelo de Toledo Petrilli, Dan Carai Maia Viola, Reynaldo Jesus Garcia

PMC · DOI: 10.1590/1413-785220263401e283136 · Acta Ortopedica Brasileira · 2026-02-13

## TL;DR

This case series evaluates treatment outcomes and recurrence rates in patients with aneurysmal bone cysts, a benign but aggressive bone tumor.

## Contribution

The study provides epidemiological data and treatment outcomes for aneurysmal bone cysts in a pediatric cohort.

## Key findings

- The overall recurrence rate of aneurysmal bone cysts was 30.4%.
- No significant association was found between recurrence and variables like sex, age, or treatment type.
- Most cysts were located in the lower limbs, and surgery with bone grafting was the most common treatment.

## Abstract

The Aneurysmal Bone Cyst (ABC) is a benign yet aggressive bone tumor. This study aimed to evaluate sex, age, tumor location, tumor size, type of treatment (surgical, infiltration, embolization), and recurrence.

Descriptive and quantitative statistical analyses were applied. The prevalence ratio and 95% confidence interval were calculated for the association between recurrence and sex, age, tumor size, Capanna's classification, and treatment type.

Twenty-three cases of ABCs were included, eleven (47.8%) females and twelve (52.2%) males. The mean age of treated patients was 11.2±1.8 years. Most cysts were located in the lower limbs (56.5%). The mean follow-up time was 42.8±14.01 months. The mean cyst diameter at the beginning of treatment was 5.58± 1.04 cm; of these, 17.4% were up to 3 cm, 43.5% from 3.1 to 6 cm, and 39.1% over 6 cm. Regarding initial treatment, 6 (26%) patients received infiltration, and in total 20 (86.9%) underwent surgery with bone grafting. The overall recurrence rate was 30.4%. No association was identified between recurrence and the variables studied (p ≥ 0.05). The epidemiological data obtained are consistent with pediatric cohorts reported in the literature.

All evaluated methods are suitable for treating aneurysmal bone cysts. 
Level of Evidence IV; Case Series.

## Linked entities

- **Diseases:** Aneurysmal Bone Cyst (MONDO:0018815)

## Full-text entities

- **Diseases:** ABC (MESH:D017824), cyst (MESH:D003560), TUMOR (MESH:D009369), bone tumor (MESH:D001859), ABCs (MESH:C579754), ANEURYSMAL BONE CYST (MESH:C566458)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12904640/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12904640/full.md

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Source: https://tomesphere.com/paper/PMC12904640