# Challenges in the Diagnosis and Treatment of Mycobacterium abscessus Infections

**Authors:** Ana Júlia Reis, Michael Andrés Abril Gómez, Mariana Quaresma de Souza, Júlia Silveira Vianna, Ivy Bastos Ramis, Pedro Eduardo Almeida da Silva

PMC · DOI: 10.1590/0037-8682-0354-2025 · Revista da Sociedade Brasileira de Medicina Tropical · 2026-02-16

## TL;DR

This paper reviews the challenges in diagnosing and treating infections caused by Mycobacterium abscessus, a type of bacteria that affects vulnerable patients.

## Contribution

The paper provides a comprehensive review of recent advancements in diagnosing and managing Mycobacterium abscessus infections.

## Key findings

- MABC infections are significant in immunocompromised patients and those with lung conditions.
- Antibiotic resistance and biocide resistance in MABC complicate treatment.
- Recent progress in diagnostic methods and treatment options is reviewed.

## Abstract

The Mycobacterium abscessus complex (MABC) includes non-tuberculous mycobacteria that are widely distributed and clinically significant. Similar to tuberculosis, MABC can lead to skin and soft tissue infections and pulmonary diseases. These infections frequently occur in outbreaks, particularly among immunocompromised patients or those with preexisting pulmonary conditions. This review examines the recent progress in essential areas that define these infections as a significant challenge in medical practice, specifically the diagnostic modalities, antibiotic treatment options, and resistance of MABC to antibiotics and biocides.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076), pulmonary diseases (MONDO:0005275)

## Full-text entities

- **Diseases:** infections (MESH:D007239), tuberculosis (MESH:D014376), skin (MESH:D012871), Mycobacterium abscessus (MESH:D009165), soft tissue infections (MESH:D018461), pulmonary diseases (MESH:D008171)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12904598/full.md

## References

116 references — full list in the complete paper: https://tomesphere.com/paper/PMC12904598/full.md

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Source: https://tomesphere.com/paper/PMC12904598