# Brazil accounts for nearly 90% of the leprosy cases in the Americas

**Authors:** Ana Flávia Sobral de Medeiros, Aline Lidiane Batista, Sidnei Miyoshi Sakamoto, Diogo Manuel Lopes de Paiva Cavalcanti, Renata Ferreira Magalhães

PMC · DOI: 10.1590/0037-8682-0276-2025 · Revista da Sociedade Brasileira de Medicina Tropical · 2026-02-16

## TL;DR

Brazil has most leprosy cases in the Americas, and the pandemic affected diagnosis and treatment, though co-infection with COVID-19 did not worsen the disease.

## Contribution

The study shows how the pandemic impacted leprosy control and treatment dropout rates in Brazil.

## Key findings

- The average weekly number of leprosy cases declined during the post-pandemic period.
- Male patients had a higher treatment dropout rate (OR, 6.32; p = 0.013).
- Of 57 patients tested for COVID-19, 21 were positive, but with no clinical aggravation.

## Abstract

Leprosy is endemic to Brazil. The Coronavirus disease 2019 (COVID-19) pandemic may have affected diagnosis and treatment.

Study in Mossoró-RN (2018-2023) analyzing epidemiological data, treatment abandonment, and COVID-19 co-infection.

The average weekly number of cases declined during the post-pandemic period. The dropout rate was higher during the acute phase. Male sex was associated with dropout (odds ratio [OR], 6.32; p = 0.013). Of the 57 patients tested for COVID-19, 21 tested positive, with no clinical aggravation.

The pandemic has affected leprosy control. Local strategies helped reduce the impact, and co-infection did not worsen the disease.

## Linked entities

- **Diseases:** leprosy (MONDO:0005124), Coronavirus disease 2019 (MONDO:0100096), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** Leprosy (MESH:D007918), infection (MESH:D007239), COVID-19 (MESH:D000086382)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12904597/full.md

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Source: https://tomesphere.com/paper/PMC12904597