# Focal Hepatic Hot Spot (‘Hot Quadrate’) Sign on Contrast‑enhanced Abdominal CT: A Telltale Pearl Indicating Superior Vena Cava (SVC) Syndrome

**Authors:** Maryse Lejoly, Louke Delrue, Koenraad J Mortele

PMC · DOI: 10.5334/jbsr.4164 · Journal of the Belgian Society of Radiology · 2026-02-10

## TL;DR

A specific liver enhancement pattern on CT scans can indicate superior vena cava syndrome.

## Contribution

A new, specific CT sign is identified for diagnosing superior vena cava syndrome.

## Key findings

- A focal hepatic hot spot in liver segment 4 is linked to SVC syndrome.
- Early vein filling of Sappey's veins is a key indicator in CT scans.
- This sign is pathognomonic for SVC syndrome.

## Abstract

Teaching point: Transient, topographically delineated, intense arterial enhancement in liver segment 4, associated with early filling of the dilated veins of Sappey, is a pathognomonic abdominal CT sign of superior vena cava (SVC) syndrome.

## Linked entities

- **Diseases:** superior vena cava syndrome (MONDO:0043287)

## Full-text entities

- **Diseases:** Superior Vena Cava (SVC) Syndrome (MESH:D013479)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12904115/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12904115/full.md

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Source: https://tomesphere.com/paper/PMC12904115