# Towards human-centric intelligent treatment planning for radiation therapy

**Authors:** Adnan Jafar, Xun Jia

PMC · DOI: 10.1038/s41746-026-02339-5 · 2026-01-10

## TL;DR

This paper proposes an AI-based framework for radiation therapy planning that aims to improve efficiency and plan quality while involving human oversight.

## Contribution

Introduces HCITP, a novel AI-driven treatment planning framework that integrates clinical guidelines and enables direct planner interaction.

## Key findings

- HCITP could reduce planning time to minutes while maintaining high-quality plans.
- The framework supports personalized treatment planning under human supervision.
- Challenges in implementation and potential solutions are outlined.

## Abstract

Current radiation therapy treatment planning is limited by suboptimal plan quality, inefficiency, and high costs. This perspective paper explores the complexity of treatment planning and introduces Human-Centric Intelligent Treatment Planning (HCITP), an AI-driven framework under human oversight, which integrates clinical guidelines, automates plan generation, and enables direct interaction with planners. We expect that HCITP will enhance efficiency, potentially reducing planning time to minutes, and will deliver personalized, high-quality plans. Challenges and potential solutions are discussed.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12902089/full.md

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Source: https://tomesphere.com/paper/PMC12902089