# Prospective randomized trial of triple port laparoscopic cholecystectomy combined with choledochoscopic common bile duct exploration and primary closure for acute abdominal pain

**Authors:** Xirang Wang, Jian Kang, Yuxiang Li, Xiaofeng Sun, Jun Zhang, Yunpeng Wu, Hehui Tao, Li Wang, Ruizhou Rong, Miao Wang, Kang Liu, Zhen Ban

PMC · DOI: 10.1038/s41598-026-37034-8 · Scientific Reports · 2026-01-22

## TL;DR

This study shows that a new surgical method for treating bile duct and gallbladder stones reduces recovery time and improves patient outcomes.

## Contribution

The study introduces a T-tube-free surgical approach combining triple-port laparoscopic cholecystectomy and primary bile duct closure.

## Key findings

- The T-tube-free group had shorter operative times, less blood loss, and faster recovery.
- Both groups had similar complication rates with no major adverse events.
- The new method aligns better with enhanced recovery after surgery (ERAS) principles.

## Abstract

To evaluate the clinical efficacy of laparoscopic common bile duct exploration (LCBDE) combined with choledochoscopy and primary closure without T-tube drainage in managing acute abdominal pain caused by choledocholithiasis (common bile duct stones, CBDS) and cholecystolithiasis with acute cholecystitis. A single-center prospective study was conducted at the Department of General Surgery, Beijing Fengtai Youanmen Hospital, from April 2024 to February 2025. Sixty-one patients with acute abdominal pain due to CBDS and cholecystolithiasis with acute cholecystitis were randomized into two groups: T-tube-free group (n = 35), Triple-port laparoscopic cholecystectomy (LC) + LCBDE with primary closure; T-tube group (n = 26), Four-port LC + LCBDE with T-tube drainage. Perioperative outcomes were compared between the groups. Baseline characteristics were comparable (all P > 0.05). The T-tube-free group demonstrated superior outcomes in operative time, intraoperative blood loss, postoperative pain, duration of abdominal drainage, and hospital stay (all P < 0.05). Each group had one case of biliary leakage, both resolved conservatively. No mortality, pancreatitis, conversion to open surgery, residual stones, biliary hemorrhage, or strictures occurred in either group. Triple-port LC combined with LCBDE and primary closure without T-tube drainage is safe and feasible for acute abdominal pain. Compared to T-tube drainage, this approach better aligns with the principles of enhanced recovery after surgery (ERAS).

## Linked entities

- **Diseases:** choledocholithiasis (MONDO:0006699), cholecystolithiasis (MONDO:0006698), acute cholecystitis (MONDO:0002155)

## Full-text entities

- **Diseases:** common bile duct stones (MESH:D042882), acute abdominal pain (MESH:D059787), biliary leakage (MESH:D003763), strictures (MESH:D003251), acute cholecystitis (MESH:D041881), blood loss (MESH:D016063), stones (MESH:D007669), cholecystolithiasis (MESH:D041761), biliary hemorrhage (MESH:D006431), postoperative pain (MESH:D010149), pancreatitis (MESH:D010195), choledocholithiasis (MESH:D042883)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12901185/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12901185/full.md

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Source: https://tomesphere.com/paper/PMC12901185